Adrenal Steroid Quantitative Panel by HPLC-MS/MS, Serum or Plasma
0092330
 
Ordering Recommendation
Mnemonic
ADSTEROID
Methodology
Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry
Performed
Mon-Fri
Reported
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
 
Collect
Serum separator tube. Also acceptable: Plain red, pink (K2EDTA), or green (sodium or lithium heparin).  
Specimen Preparation
Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1.2 mL serum or plasma to an ARUP Standard Transport Tube and freeze immediately. (Min: 0.6 mL)  
Storage/Transport Temperature
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.  
Unacceptable Conditions
Refrigerated or room temperature specimens.  
Remarks
 
Stability
After separation from cells: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 6 months  
Reference Interval
Test Number Components Reference Interval
009233111-​Deoxycortisol Quantitative by HPLC-​MS/MS, Serum or Plasma Effective August 19, 2013
Age Female Male
Premature (26-​28 weeks) 110-​1376 ng/dL 110-​1376 ng/dL
Premature (29-​36 weeks) 70-​455 ng/dL 70-​455 ng/dL
Full Term (1-​5 months) 10-​200 ng/dL 10-​200 ng/dL
6-​11 months 10-​276 ng/dL 10-​276 ng/dL
1-​3 years 7-​247 ng/dL 7-​202 ng/dL
4-​6 years 8-​291 ng/dL 8-​235 ng/dL
7-​9 years Less than or equal to 94 ng/dL Less than or equal to 120 ng/dL
10-​12 years Less than or equal to 123 ng/dL Less than or equal to 92 ng/dL
13-​15 years Less than or equal to 107 ng/dL Less than or equal to 95 ng/dL
16-​17 years Less than or equal to 47 ng/dL Less than or equal to 106 ng/dL
18 years and older Less than 33 ng/dL Less than 50 ng/dL
Tanner Stage I Less than or equal to 94 ng/dL Less than or equal to 105 ng/dL
Tanner Stage II Less than or equal to 136 ng/dL Less than or equal to 108 ng/dL
Tanner Stage III Less than or equal to 99 ng/dL Less than or equal to 111 ng/dL
Tanner Stage IV & V Less than or equal to 50 ng/dL Less than or equal to 83 ng/dL
After metyrapone stimulation Greater than 8000 ng/dL Greater than 8000 ng/dL
009233217-​Hydroxyprogesterone Quantitative by HPLC-​MS/MS, Serum or Plasma Effective August 19, 2013
Age Female Male
Premature (26-​28 weeks) 124-​841 ng/dL 124-​841 ng/dL
Premature (29-​35 weeks) 26-​568 ng/dL 26-​568 ng/dL
Full term Day 3 7-​77 ng/dL 7-​77 ng/dL
4 days-​30 days 7-​106 ng/dL Less than 200 ng/dL
1 month-​2 months 13-​106 ng/dL Less than 200 ng/dL
3 months-​5 months 13-​106 ng/dL 3-​90 ng/dL
6 months-​1 year Less than or equal to 148 ng/dL Less than or equal to 148 ng/dL
2-​3 years Less than or equal to 256 ng/dL Less than or equal to 228 ng/dL
4-​6 years Less than or equal to 299 ng/dL Less than or equal to 208 ng/dL
7-​9 years Less than or equal to 71 ng/dL Less than or equal to 63 ng/dL
10-​12 years Less than or equal to 129 ng/dL Less than or equal to 79 ng/dL
13-​15 years 9-​208 ng/dL 9-​140 ng/dL
16-​17 years Less than or equal to 178 ng/dL 24-​192 ng/dL
18 years and older Less than 207 ng/dL Less than 139 ng/dL
Follicular 15-​70 ng/dL Does Not Apply
Luteal 35-​290 ng/dL Does Not Apply
Tanner Stage I Less than or equal to 74 ng/dL Less than or equal to 62 ng/dL
Tanner Stage II Less than or equal to 164 ng/dL Less than or equal to 104 ng/dL
Tanner Stage III 13-​209 ng/dL Less than or equal to 151 ng/dL
Tanner Stage IV-​V 7-​170 ng/dL 20-​173 ng/dL
009233317-​Hydroxypregnenolone Quantitative by LC-​MS/MS, Serum or Plasma
Age Female Male
Premature (26-​28 weeks) 1219-​9799 ng/dL 1219-​9799 ng/dL
Premature (29-​36 weeks) 346-​8911 ng/dL 346-​8911 ng/dL
Full Term (1-​5 months) 229-​3104 ng/dL 229-​3104 ng/dL
6-​12 months less than or equal to 917ng/dL less than or equal to 917ng/dL
13-​23 months less than or equal to 592 ng/dL less than or equal to 592 ng/dL
2-​4 years less than or equal to 280 ng/dL less than or equal to 249 ng/dL
5-​6 years less than or equal to 350 ng/dL less than or equal to 319 ng/dL
7-​9 years less than or equal to 212 ng/dL less than or equal to 187 ng/dL
10-​12 years less than or equal to 398 ng/dL less than or equal to 392 ng/dL
13-​15 years less than or equal to 407 ng/dL 35-​465 ng/dL
16-​17 years less than or equal to 423 ng/dL 32-​478 ng/dL
18 years and older Less than 226 ng/dL Less than 442 ng/dL
Tanner Stage I less than or equal to 235 ng/dL less than or equal to 208 ng/dL
Tanner Stage II less than or equal to 367 ng/dL less than or equal to 355 ng/dL
Tanner Stage III less than or equal to 430 ng/dL less than or equal to 450 ng/dL
Tanner Stage IV-​V less than or equal to 412 ng/dL 35-​478 ng/dL
0092334Pregnenolone by LC-​MS/MS, Serum or Plasma
Age Female Male
6-​12 months 13-​327 ng/dL 13-​327 ng/dL
13-​23 months 12-​171 ng/dL 12-​171 ng/dL
2-​4 years 15-​125 ng/dL 10-​125 ng/dL
5-​6 years 13-​191 ng/dL 10-​156 ng/dL
7-​9 years 14-​150 ng/dL 13-​205 ng/dL
10-​12 years 19-​220 ng/dL 15-​151 ng/dL
13-​15 years 22-​210 ng/dL 18-​197 ng/dL
16-​17 years 22-​229 ng/dL 17-​228 ng/dL
18 years and older 15-​132 ng/dL 23-​173 ng/dL
Tanner Stage I 15-​171 ng/dL 13-​156 ng/dL
Tanner Stage II 22-​229 ng/dL 12-​143 ng/dL
Tanner Stage III 34-​215 ng/dL 16-​214 ng/dL
Tanner Stage IV-​V 26-​235 ng/dL 19-​201 ng/dL
Interpretive Data


See Compliance Statement B: www.aruplab.com/CS
Note
CPT Code(s)
82634; 83498; 84143; 84140
Components
Component Test Code*Component Chart Name
009233111-Deoxycortisol, HPLC-MS/MS
009233217-Hydroxyprogesterone, HPLC-MS/MS
009233317-Hydroxypregnenolone Quant, MS/MS, Ser
0092334Pregnenolone
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at interface.support@aruplab.com.
Cross References
  • 11-Deoxycortisol
  • 17-Hydroxypregnenolone
  • 17-Hydroxyprogesterone
  • CAH
  • Congenital Adrenal Hyperplasia
  • Pregnenolone