Adrenal Steroid Quantitative Panel by HPLC-MS/MS, Serum or Plasma
0092330
Ordering Recommendation
 
Mnemonic
ADSTEROID
Methodology
Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry
Performed
Mon-Fri
Reported
1-4 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Serum separator tube. Also acceptable: Plain red, pink (K2EDTA), or green (sodium or lithium heparin).  
Specimen Preparation
Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1.2 mL serum or plasma to an ARUP Standard Transport Tube and freeze immediately. (Min: 0.6 mL)  
Storage/Transport Temperature
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.  
Unacceptable Conditions
Refrigerated or room temperature specimens.  
Remarks
  
Stability
After separation from cells: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 6 months  
Reference Interval
 
 
Test Number Components Reference Interval
009233111-​Deoxycortisol Quantitative by HPLC-​MS/MS, Serum or Plasma Effective August 19, 2013
 
Age Female Male
Premature (26-​28 weeks) 110-​1376 ng/dL 110-​1376 ng/dL
Premature (29-​36 weeks) 70-​455 ng/dL 70-​455 ng/dL
Full Term (1-​5 months) 10-​200 ng/dL 10-​200 ng/dL
6-​11 months 10-​276 ng/dL 10-​276 ng/dL
1-​3 years 7-​247 ng/dL 7-​202 ng/dL
4-​6 years 8-​291 ng/dL 8-​235 ng/dL
7-​9 years Less than or equal to 94 ng/dL Less than or equal to 120 ng/dL
10-​12 years Less than or equal to 123 ng/dL Less than or equal to 92 ng/dL
13-​15 years Less than or equal to 107 ng/dL Less than or equal to 95 ng/dL
16-​17 years Less than or equal to 47 ng/dL Less than or equal to 106 ng/dL
18 years and older Less than 33 ng/dL Less than 50 ng/dL
Tanner Stage I Less than or equal to 94 ng/dL Less than or equal to 105 ng/dL
Tanner Stage II Less than or equal to 136 ng/dL Less than or equal to 108 ng/dL
Tanner Stage III Less than or equal to 99 ng/dL Less than or equal to 111 ng/dL
Tanner Stage IV & V Less than or equal to 50 ng/dL Less than or equal to 83 ng/dL
After metyrapone stimulation Greater than 8000 ng/dL Greater than 8000 ng/dL
 
009233217-​Hydroxyprogesterone Quantitative by HPLC-​MS/MS, Serum or Plasma Effective August 19, 2013
 
Age Female Male
Premature (26-​28 weeks) 124-​841 ng/dL 124-​841 ng/dL
Premature (29-​35 weeks) 26-​568 ng/dL 26-​568 ng/dL
Full term Day 3 7-​77 ng/dL 7-​77 ng/dL
4 days-​30 days 7-​106 ng/dL Less than 200 ng/dL
1 month-​2 months 13-​106 ng/dL Less than 200 ng/dL
3 months-​5 months 13-​106 ng/dL 3-​90 ng/dL
6  months-​1 year Less than or equal to 148 ng/dL Less than or equal to 148 ng/dL
2-​3 years Less than or equal to 256 ng/dL Less than or equal to 228 ng/dL
4-​6 years Less than or equal to 299 ng/dL Less than or equal to 208 ng/dL
7-​9 years Less than or equal to 71 ng/dL Less than or equal to 63 ng/dL
10-​12 years Less than or equal to 129 ng/dL Less than or equal to 79 ng/dL
13-​15 years 9-​208 ng/dL 9-​140 ng/dL
16-​17 years Less than or equal to 178 ng/dL 24-​192 ng/dL
18 years and older Less than 207 ng/dL Less than 139 ng/dL
Follicular 15-​70 ng/dL Does Not Apply
Luteal 35-​290 ng/dL Does Not Apply
Tanner Stage I Less than or equal to 74 ng/dL Less than or equal to 62 ng/dL
Tanner Stage II Less than or equal to 164 ng/dL Less than or equal to 104 ng/dL
Tanner Stage III 13-​209 ng/dL Less than or equal to 151 ng/dL
Tanner Stage IV-​V 7-​170 ng/dL 20-​173 ng/dL
009233317-​Hydroxypregnenolone Quantitative by LC-​MS/MS, Serum or Plasma  
 
Age Female Male
Premature (26-​28 weeks) 1219-​9799 ng/dL 1219-​9799 ng/dL
Premature (29-​36 weeks) 346-​8911 ng/dL 346-​8911 ng/dL
Full Term (1-​5 months) 229-​3104 ng/dL 229-​3104 ng/dL
6-​12 months less than or equal to 917ng/dL less than or equal to 917ng/dL
13-​23 months less than or equal to 592 ng/dL less than or equal to 592 ng/dL
2-​4 years less than or equal to 280 ng/dL less than or equal to 249 ng/dL
5-​6 years less than or equal to 350 ng/dL less than or equal to 319 ng/dL
7-​9 years less than or equal to 212 ng/dL less than or equal to 187 ng/dL
10-​12 years less than or equal to 398 ng/dL less than or equal to 392 ng/dL
13-​15 years less than or equal to 407 ng/dL 35-​465 ng/dL
16-​17 years less than or equal to 423 ng/dL 32-​478 ng/dL
18 years and older Less than 226 ng/dL Less than 442 ng/dL
Tanner Stage I less than or equal to 235 ng/dL less than or equal to 208 ng/dL
Tanner Stage II less than or equal to 367 ng/dL less than or equal to 355 ng/dL
Tanner Stage III less than or equal to 430 ng/dL less than or equal to 450 ng/dL
Tanner Stage IV-​V less than or equal to 412 ng/dL 35-​478 ng/dL
0092334Pregnenolone by LC-​MS/MS, Serum or Plasma  
 
Age Female Male
6-​12 months 13-​327 ng/dL 13-​327 ng/dL
13-​23 months 12-​171 ng/dL 12-​171 ng/dL
2-​4 years 15-​125 ng/dL 10-​125 ng/dL
5-​6 years 13-​191 ng/dL 10-​156 ng/dL
7-​9 years 14-​150 ng/dL 13-​205 ng/dL
10-​12 years 19-​220 ng/dL 15-​151 ng/dL
13-​15 years 22-​210 ng/dL 18-​197 ng/dL
16-​17 years 22-​229 ng/dL 17-​228 ng/dL
18 years and older 15-​132 ng/dL 23-​173 ng/dL
Tanner Stage I 15-​171 ng/dL 13-​156 ng/dL
Tanner Stage II 22-​229 ng/dL 12-​143 ng/dL
Tanner Stage III 34-​215 ng/dL 16-​214 ng/dL
Tanner Stage IV-​V 26-​235 ng/dL 19-​201 ng/dL
Interpretive Data


See Compliance Statement B: www.aruplab.com/CS
Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
 
Note
 
CPT Code(s)
82634; 83498; 84143; 84140
Components
Component Test Code*Component Chart Name
009233111-Deoxycortisol, HPLC-MS/MS
009233217-Hydroxyprogesterone, HPLC-MS/MS
009233317-Hydroxypregnenolone Quant, MS/MS, Ser
0092334Pregnenolone
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • 11-Deoxycortisol
  • 17-Hydroxypregnenolone
  • 17-Hydroxyprogesterone
  • CAH
  • Congenital Adrenal Hyperplasia
  • Pregnenolone