Calprotectin, Fecal
0092303
Ordering Recommendation
May be used to differentiate inflammatory bowel disease (IBD) from irritable bowel syndrome (IBS) and other functional disorders of the intestinal tract; may also be used for monitoring IBD activity.
Mnemonic
CALPRO
Methodology
Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Mon-Sat
Reported
1-3 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Stool.  
Specimen Preparation
Transfer 5 g stool to an unpreserved stool transport vial (ARUP Supply #40910). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 1 g)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Specimens in media or preservatives.  
Remarks
  
Stability
Ambient: 11 days; Refrigerated: 11 days; Frozen: 1 year  
Reference Interval
50 µg/g or less: Normal
51-120 µg/g: Borderline elevated, test should be re-evaluated in 4-6 weeks.
121 µg/g or greater: Abnormal, suggestive of inflammatory bowel disease (IBD).  
Interpretive Data
 
Note
Fecal Calprotectin is an indicator of the presence of neutrophils in stool and is not specific for IBD. Other intestinal ailments including GI infections and colorectal cancer can result in elevated concentrations of calprotectin. The diagnosis of IBD cannot be established solely on the basis of a positive calprotectin result. Patients with IBD fluctuate between active and inactive stages of disease. Calprotectin results may also fluctuate. GI bleeding of as much as 100 mL per day will increase the fecal calprotectin concentration by only 15 µg/g.
CPT Code(s)
83993
Components
Component Test Code*Component Chart Name
0092304Calprotectin, Fecal
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Fecal Calprotectin
  • Stool Calprotectin