Feedback
Chlorpromazine
0090870
Ordering Recommendation
Optimize drug therapy and monitor patient adherence.
Mnemonic
CHLORP
Methodology
Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Performed
Wed, Sat
Reported
1-5 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.  
Collect
Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2EDTA).  
Specimen Preparation
Separate serum or plasma from cells within 2 hours of collection. Transfer 2 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 1 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Whole blood. Light blue (citrate) or yellow (SPS or ACD solution).  
Remarks
 
Stability
After separation from cells: Ambient: 12 hours; Refrigerated: 72 hours; Frozen: 5 days  
Reference Interval
Effective February 19, 2013
Child (0 - 11 years)
Adult (12 years and older)
Therapeutic Range30-80 ng/mL50-300 ng/mL
Toxic LevelGreater than 200 ng/mLGreater than 750 ng/mL

Interpretive Data
Toxic concentrations may cause drowsiness, coma, hypotension, tachycardia and seizures. Large daily doses of chlorpromazine may cause phenothiazine sudden death syndrome.


Note
CPT Code(s)
80342 (Alt code: G0480)
Components
Component Test Code*Component Chart NameLOINC
0090870Chlorpromazine3471-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Largactil
  • Ormazine
  • Thorazine
  • Thorazine Spansule