Drug Screen (Nonforensic), Comprehensive, Serum and Urine
Ordering Recommendation
Submit With Order
Immunoassay/Gas Chromatography-Mass Spectrometry/Liquid Chromatography-Tandem Mass Spectrometry
1-2 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
First morning catch of urine, if possible.  
Plain red AND fresh random urine.  
Specimen Preparation
Transfer 6 mL serum to ARUP Standard Transport Tubes (Min: 5.5 mL) AND transport 25 mL urine. (Min: 12 mL)  
Storage/Transport Temperature
Unacceptable Conditions
Serum: After separation from cells: Ambient: 48 hours; Refrigerated: 1 week; Frozen: 2 months
Urine: Ambient: 5 days; Refrigerated: 2 weeks; Frozen 2 months  
Reference Interval
Interpretive Data
The following drugs or drug classes may be detected in this analysis:

SERUM: Acetaminophen, alcohols, barbiturates, benzodiazepines, carbamazepine, carisoprodol, disopyramide, meprobamate, phenytoin, primidone, salicylate, theophylline, tricyclic and other antidepressants.

URINE: Acetaminophen, alcohols, barbiturates, benzodiazepines, carbamazepine, carisoprodol, chlorpheniramine, cocaine & metabolites, diphenhydramine, ethchlorvynol, ibuprofen, lidocaine, meprobamate, narcotics & synthetics, phencyclidine, phenothiazines, phenytoin, primidone & metabolites, pyrilamine, salicylate, sympathomimetic amines, theophylline, tricyclic and other antidepressants, trimethoprim.
This test is not optimized for most drugs of abuse (amphet/methamphet, barbiturates, benzodiazepines, cocaine, methadone, opiates, propoxyphene, PCP, THC); instead refer to Drug Screen 1, Serum or Plasma (0091191), and/or Drugs of Abuse 9 Panel, Urine - Screen & Confirmation/Quantitation (0092186), or Drugs of Abuse 7 Panel, Urine - Screen & Confirmation/Quantitation (0092184).
CPT Code(s)
80101 (HCPCS:G0431); 80100; 80100; 80100; 80101
Component Test Code*Component Chart Name
0090499Drug Screen (Nonforensic), Serum
0090500Drug Screen (Nonforensic), Urine, Qual
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Cross References
  • Drug Analysis, Comprehensive
  • Drug Screen (Nonforensic), Serum
  • Drug Screen (Nonforensic), Urine, Qual
  • Multiple Drug Analysis
  • Tox Screen
  • Urine Drug Screen