Fluoxetine and Metabolite
0090450
Ordering Recommendation
Submit With Order
Mnemonic
FLUOX
Methodology
Quantitative High Performance Liquid Chromatography
Performed
Tue, Sun
Reported
1-6 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.  
Collect
Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2EDTA).  
Specimen Preparation
Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).  
Remarks
 
Stability
After separation from cells: Ambient: 12 hours; Refrigerated: 5 days; Frozen: 1 month  
Reference Interval
Effective February 18, 2014
Fluoxetine Dose-​Related Range:
100-​800 ng/mL
Norfluoxetine Dose-​Related Range:
100-​600 ng/mL
Fluoxetine and Norfluoxetine Toxic: Greater than 2000 ng/mL
Interpretive Data
Dose-related ranges for fluoxetine/norfluoxetine are based on a 20 to 60 mg dose/day. Adverse effects may include insomnia, headache and somnolence.
Note
CPT Code(s)
80299
Components
Component Test Code*Component Chart Name
0090451Fluoxetine
0090452Norfluoxetine
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Cross References
  • Fluoxetine Hydrochloride
  • Fluoxetine/Norfluoxetine
  • Norfluoxetine
  • Oxactin
  • Prozac
  • Rapiflux
  • Sarafem
  • Selfemra