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Tricyclic Antidepressant Detection
0090307
Ordering Recommendation
Mnemonic
S TAD
Methodology
Enzyme Immunoassay
Performed
Sun-Sat
Reported
Within 24 hours
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Plain red.  
Specimen Preparation
Separate serum from cells within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Separator tubes.  
Remarks
 
Stability
After separation from cells: Ambient: 24 hours; Refrigerated: 1 month; Frozen: 1 year  
Reference Interval
Negative
Interpretive Data
This result represents the total level of all detectable tricyclic antidepressants present. Tricyclic antidepressants detectable with this assay include: amitriptyline, clomipramine, desipramine, doxepin, imipramine, nortriptyline, protriptyline, and trimipramine.

Levels of tricyclic antidepressants in the therapeutic range may not be detectable.

False-positive results may occur with the following drugs: Seroquel® (quetiapine fumarate), Trileptal® (oxcarbazepine), Benadryl® (diphenhydramine) at toxic concentrations, Flexeril (cyclobenzaprine), Thioridazine, and Thorazine® (chlorpromazine).


Note
CPT Code(s)
80301 (Alt code: G0479)
Components
Component Test Code*Component Chart NameLOINC
0090307Tricyclic Antidepressant Detection4073-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • amitriptyline
  • desipramine
  • domipramine
  • doxepin
  • imipramine
  • nortriptyline
  • protriptyline
  • Tricyclic Antidepressants, Total, detection
  • trimipramine