Tricyclic Antidepressant Detection
0090307
Ordering Recommendation
 
Mnemonic
S TAD
Methodology
Enzyme Immunoassay
Performed
Sun-Sat
Reported
Within 24 hours  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Plain red.  
Specimen Preparation
Separate serum from cells within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Separator tubes.  
Remarks
  
Stability
After separation from cells: Ambient: 24 hours; Refrigerated: 1 month; Frozen: 1 year  
Reference Interval
Negative  
Interpretive Data
This result represents the total level of all detectable tricyclic antidepressants present. Tricyclic antidepressants detectable with this assay include: amitriptyline, clomipramine, desipramine, doxepin, imipramine, nortriptyline, protriptyline, and trimipramine.

Levels of tricyclic antidepressants in the therapeutic range may not be detectable.

False-positive results may occur with the following drugs: Seroquel® (quetiapine fumarate), Trileptal® (oxcarbazepine), Benadryl® (diphenhydramine) at toxic concentrations, Flexeril (cyclobenzaprine), Thioridazine, and Thorazine® (chlorpromazine).  
Note
 
CPT Code(s)
80101
Components
Component Test Code*Component Chart NameLOINC
0090307Tricyclic Antidepressant Detection4073-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • amitriptyline
  • desipramine
  • domipramine
  • doxepin
  • imipramine
  • nortriptyline
  • protriptyline
  • Tricyclic Antidepressants, Total, detection
  • trimipramine