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Epithelial Cell Surface Antibody IgG
0090266
Ordering Recommendation

Monitor patient with pemphigus who has positive IgG cell surface antibodies, but normal IgG desmoglein 1 and/or 3 antibody levels. For initial diagnosis and disease monitoring, the preferred test is Pemphigus Antibody Panel - Epithelial Cell Surface Antibodies and Desmoglein 1 and Desmoglein 3 Antibodies, IgG (0090650); panel components include IgG epithelial cell surface antibodies and IgG desmoglein 1 and 3.
May use to screen for pemphigus or pemphigoid; however, this test has decreased sensitivity and specificity when compared to Pemphigus Antibody Panel - Epithelial Cell Surface Antibodies and Desmoglein 1 and Desmoglein 3 Antibodies, IgG (0090650) or Pemphigoid Antibody Panel - Epithelial Basement Membrane Zone Antibodies, IgG and IgA, BP180 and BP230 Antibodies, IgG (0092001).

Mnemonic
IGG EPI AB
Methodology
Indirect Fluorescent Antibody
Performed
Varies
Reported
4-9 days
New York DOH Approval Status
This test is New York DOH approved.
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Plain red or serum separator tube (SST). 
Specimen Preparation
Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Hemolyzed or lipemic specimens. 
Remarks
 
Stability
Ambient: 1 week; Refrigerated: 2 weeks; Frozen: Indefinitely 
Reference Interval
By report
Interpretive Data


Note
For specimens less than 0.5 mL, call the Immunodermatology Laboratory at (866) 266-5699.
Components
Component Test Code*Component Chart NameLOINC
0090268Epithelial Cell Surface Ab IgG
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases

Performed at UUHC-Immunodermatology