Ordering Recommendation

Detect overdose. Optimize drug therapy and monitor patient adherence.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Plain red. Also acceptable: Green (sodium heparin).

Specimen Preparation

Separate serum from cells within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Lipemic specimens. Gel separator tubes are not acceptable, regardless of the tube additive.

Remarks

Lipemic specimens may cause an underestimation of Theophylline level

Stability

After separation from cells: Ambient: 8 hours; Refrigerated: 8 days; Frozen: 3 months

Methodology

Enzyme Immunoassay

Performed

Sun-Sat

Reported

Within 24 hours

Reference Interval

0-5 months: 6.0-12.0 µg/mL
  Toxic: 20.1 µg/mL or greater 

6 months and older: 10.0-20.0 µg/mL
  Toxic: 25.1 µg/mL or greater

Interpretive Data



Compliance Category

FDA

Note

Not recommended for treatment of neonatal apnea.

Hotline History

N/A

CPT Codes

80198

Components

Component Test Code* Component Chart Name LOINC
0090265 Theophylline 4049-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Aminophylline
  • Elixophylin
  • Elixophyllin
Theophylline