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0090202
Primidone and Metabolite
PRIM
Ordering Recommendation
Optimize drug therapy and monitor patient adherence; the active metabolite of primidone is phenobarbital.
New York DOH Approval Status
This test is New York state approved.
Specimen Required
Patient Preparation
Collect
Plain red. Also acceptable: Green (sodium heparin).
Specimen Preparation
Allow specimen to clot completely at room temperature. Separate serum from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP standard transport tube. (Min: 0.8 mL)
Storage/Transport Temperature
Refrigerated.
Unacceptable Conditions
Separator tubes.
Remarks
Stability
After separation from cells: Ambient: 1 week; Refrigerated: 1 week; Frozen: 1 month
Methodology
Immunoassay
Performed
Sun-Sat
Reported
Within 24 hours
Reference Interval
| Test Number |
Components |
Reference Interval |
||||||
|---|---|---|---|---|---|---|---|---|
| Phenobarbital |
|
|||||||
| Primidone (Mysoline) | 5.0-12 µg/mL |
Interpretive Data
Primidone concentrations greater than 15 µg/mL in conjunction with therapeutic levels of phenobarbital may be associated with toxicity.
| Component | Age | Interpretive Data (µg/mL) |
|---|---|---|
| Phenobarbital | 0-2 months | Toxic: 40.1 or greater |
| Phenobarbital | 3 months and older | Toxic: 50.1 or greater |
Compliance Category
FDA
Note
Hotline History
N/A
CPT Codes
80188; 80184
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0090230 | Phenobarbital | 3948-7 |
| 0090240 | Primidone (Mysoline) | 3978-4 |
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
- Luminal
- Mysoline
- Mysoline Primidon)
- Phenobarbital
- Primidone
Primidone and Metabolite
