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Primidone and Metabolite
0090202
Ordering Recommendation
Mnemonic
PRIM
Methodology
Immunoassay
Performed
Sun-Sat
Reported
Within 24 hours
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Plain red. Also acceptable: Green (sodium heparin). 
Specimen Preparation
Allow specimen to clot completely at room temperature. Separate serum from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.8 mL) 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Separator tubes. 
Remarks
 
Stability
After separation from cells: Ambient: 1 week; Refrigerated: 1 week; Frozen: 1 month 
Reference Interval
Test Number
Components
Reference Interval
0090230Phenobarbital0-2 months: 15.0-30.0 µg/mL
  Toxic: 40.1 µg/mL or greater 
3 months and older: 15.0-40.0 µg/mL
  Toxic: 50.1 µg/mL or greater
 Primidone (Mysoline)5-12 µg/mL

Interpretive Data
Primidone concentrations greater than 15 µg/mL in conjunction with therapeutic levels of phenobarbital may be associated with toxicity.

Note
CPT Code(s)
80188; 80184
Components
Component Test Code*Component Chart NameLOINC
0090230Phenobarbital3948-7
0090240Primidone (Mysoline)3978-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Luminal
  • Mysoline
  • Mysoline Primidon)
  • Phenobarbital
  • Primidone