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Procainamide and NAPA
0090151
Ordering Recommendation
Mnemonic
PROC
Methodology
Immunoassay
Performed
Sun-Sat
Reported
Within 24 hours
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Plain red. Also acceptable: Green (sodium heparin).  
Specimen Preparation
Separate serum from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
EDTA plasma. Gray (sodium fluoride/potassium oxalate) or separator tubes or gels.  
Remarks
 
Stability
After separation from cells: Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 6 months  
Reference Interval
Test Number
Components
Reference Interval
 N-acetylprocainamide (NAPA)6.0-20.0 µg/mL
Toxic: 35.1 µg/mL or greater 
 Procainamide4.0-10.0 µg/mL
Toxic: 12.1 µg/mL or greater

Interpretive Data
The commonly expected therapeutic range for the sum of NAPA and Procainamide is 5-30 ug/mL. However, the concentration of NAPA is dependent on many factors, including; time of last procainamide dose, mode of administration, concomitant drug therapy, sample condition, time of sample collection and individual variations in absorption, biotransformation, distribution and excretion. Therapeutic ranges are provided only as a guide for interpretation along with other clinical symptoms and patient history.


Note
CPT Code(s)
80192
Components
Component Test Code*Component Chart NameLOINC
0090175N-acetylprocainamide (NAPA)3834-9
0090235Procainamide3982-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • N-Acetyl Procainamide
  • NAPA
  • Pronestyl