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Clonazepam
0090055
Ordering Recommendation
Optimize drug therapy and monitor patient adherence.
Mnemonic
CLON
Methodology
Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Performed
Tue, Fri
Reported
1-5 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration  
Collect
Gray (Potassium Oxalate/Sodium Fluoride). Also acceptable: Plain Red, Green (Sodium Heparin), Lavender (K2 or K3EDTA) or pink (K2EDTA).  
Specimen Preparation
Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 2 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 1 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Gel separator tubes. Plasma or whole blood collected in light blue (sodium citrate). Hemolyzed specimens.  
Remarks
 
Stability
After separation from cells: Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 3 years (Avoid repeated freeze/thaw cycles).  
Reference Interval
Effective November 18, 2013
Dose-Related Range20-70 ng/mL - Dose (Adult) 1-8 mg/d
ToxicGreater than 80 ng/mL

Interpretive Data
Adverse effects may include drowsiness, headache, fatigue and ataxia.


Note
CPT Code(s)
80346 (Alt code: G0480)
Components
Component Test Code*Component Chart NameLOINC
0090055Clonazepam3494-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Clonazepam Metabolite, Quantitative, with medMATCH, Urine
  • Clonopin, S
  • Klonopin
  • Klonopin Wafers
  • Nitrazepam
  • Nitrozepane
  • Rivotril