Maternal Screening, Sequential, Specimen #2
Ordering Recommendation
Requires a previously submitted first trimester specimen, Maternal Screening, Sequential, Specimen #1 (0081293).
First trimester. Screens for DS and T18.
Second trimester. Screens for DS, T18, and ONTD.
Requires NT measurement performed by an ultrasonographer certified by the Fetal Medicine Foundation (FMF) or Nuchal Translucency Quality Review (NTQR).
Risks provided in both first and second trimesters.
Quantitative Chemiluminescent Immunoassay
2-4 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Requires a previously submitted first trimester specimen, Maternal Screening, Sequential, Specimen #1 (ARUP test code 0081293). Specimen must be drawn between 15 weeks, 0 days and 24 weeks, 6 days gestation.  
Serum separator tube or plain red.  
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 3 mL serum to an ARUP Standard Transport Tube. (Min: 1 mL)  
Storage/Transport Temperature
Unacceptable Conditions
Plasma. Specimens exposed to repeated freeze/thaw cycles. Hemolyzed specimens.  
The patient demographic information provided with the Sequential, Specimen #1 will be used to calculate the risks for this report. No new demographic information is required.  
After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 year  
Reference Interval
By report
Includes AFP, hCG, Estriol, Inhibin A, and previous PAPP-A.
Intervals are based upon weeks of gestation.
Interpretive Data
Refer to report

CPT Code(s)
Component Test Code*Component Chart NameLOINC
0080021Patient's AFP1834-1
0080241Estimated Due Date11778-8
0080267MoM for DIA35738-4
0080268Patient's DIA23883-2
0080917Maternal Weight29463-7
0080918MoM for AFP20450-3
0080920Maternal Screen Interpretation49586-1
0080924Insulin Req Maternal Diabetes44877-9
0080925Family Hx Neural Tube Defect8670-2
0080926Maternal Race21484-1
0080927Number of Fetuses11878-6
0080932Maternal Age At Delivery21612-7
0080935Patient's hCG19080-1
0080937MoM For hCG20465-1
0080938Gestational Age (Exact)18185-9
0080941Patient's uE32250-9
0080943MoM for uE320466-9
0081065Nuchal Translucency (NT)12146-7
0081066Crown Rump Length11957-8
0081067Patient's PAPP-A32046-5
0081068MoM for PAPP-A32123-2
0081069Sonographer Certification #49089-6
0081070Sonographer Name49088-8
0081071Ultrasound Date34970-4
0081074MoM for NT49035-9
0081158Family History of Aneuploidy32435-0
2002857EER Maternal Screening, Seq, Spec 211526-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • Maternal Serum Sequential Screen
  • second trimester screen
  • Sequential Screening
  • Serum Stepwise Sequential Screen
  • Stepwise Maternal Screen
  • Stepwise Sequential