Oligoclonal Bands in CSF and Serum
Sensitive screening test for multiple sclerosis. Preferred test is Oligoclonal Band Profile (0080440).
Qualitative Isoelectric Focusing/Electrophoresis
Mon, Wed, Fri
New York DOH Approval Status
This test is New York DOH approved.
- Patient Preparation
- CSF AND serum separator tube. Serum specimen should be drawn within 48 hours of CSF collection.
- Specimen Preparation
- Allow serum to clot completely at room temperature. Separate serum from cells ASAP or within 2 hours of collection. Transport 1.5 mL CSF (Min: 0.7 mL) AND transfer 1 mL serum to an ARUP Standard Transport Tube (Min: 0.5 mL).
- Storage/Transport Temperature
- Unacceptable Conditions
- Specimens must be assayed together for interpretation.
- Ambient: 8 hours; Refrigerated: 1 week; Frozen: 1 month
Effective August 6, 2012
|Test Number||Components||Reference Interval|
|0081139||Oligoclonal Bands, CSF||Negative|
|2005461||Oligoclonal Bands Number, CSF||0-1 Bands|
This test reports only the number of oligoclonal bands. A patient is considered positive for CSF oligoclonal bands if there are two or more bands in the CSF immunoglobulin region that are not present in the serum. In order to confirm local production of oligoclonal IgG in CSF, a matched serum sample is required. Oligoclonal bands present in CSF, but not in serum, indicate central nervous system production. Oligoclonal bands are performed using isoelectric focusing and immunofixation.
|Component Test Code*||Component Chart Name|
|0081139||Oligoclonal Bands, CSF|
|2005461||Oligoclonal Bands Number, CSF|
|2005464||Oligoclonal Bands Interpretation|
- Oligoclonal Bands Only (Oligoclonal Bands in CSF & Serum)