Sensitive screening test for multiple sclerosis. Preferred test is Oligoclonal Band Profile (0080440
Qualitative Isoelectric Focusing/Electrophoresis
This test is New York DOH approved.
This test reports only the number of oligoclonal bands. A patient is considered positive for CSF oligoclonal bands if there are two or more bands in the CSF immunoglobulin region that are not present in the serum. In order to confirm local production of oligoclonal IgG in CSF, a matched serum sample is required. Oligoclonal bands present in CSF, but not in serum, indicate central nervous system production. Oligoclonal bands are performed using isoelectric focusing and immunofixation.