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Carnitine Panel
0081110
Ordering Recommendation
Diagnose and monitor for fatty acid oxidation disorders and organic acidemias. Use in conjunction with urine organic acids and acylglycines testing.
Mnemonic
CARNPAN
Methodology
Tandem Mass Spectrometry
Performed
Tue, Thu, Sat
Reported
2-7 days
New York DOH Approval Status
This test is New York DOH approved.
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Green (sodium or lithium heparin). Also acceptable: Plain red.  
Specimen Preparation
Separate plasma or serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum or plasma to an ARUP Standard Transport Tube and freeze immediately. (Min: 0.2 mL) Avoid hemolysis.  
Storage/Transport Temperature
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.  
Unacceptable Conditions
Room temperature specimens. Specimens that have been refrigerated for greater than 12 hours. Grossly hemolyzed specimens.  
Remarks
Clinical information is needed for appropriate interpretation. Additional required information includes age, gender, diet (e.g., TPN therapy), drug therapy, and family history. Biochemical Genetics Patient History Form is available on the ARUP Web site at http://www.aruplab.com/patienthistory or by contacting ARUP Client Services.  
Stability
After separation from cells: Ambient: Unacceptable; Refrigerated: 12 hours; Frozen: 1 month  
Reference Interval
Reports include age appropriate reference interval and interpretation.
Test Number
Components
Reference Interval
0080067Carnitine, Total
AgeTotal Carnitine
1-31 days21-83 µmol/L
32 days-12 months38-73 µmol/L
13 months-6 years35-90 µmol/L
7 years-20 years31-78 µmol/L
21 years or older34-86 µmol/L

0080065Carnitine, FreeEffective May 16, 2011
AgeFree Carnitine
1-31 days15-55 µmol/L
32 days-12 months29-61 µmol/L
13 months-6 years25-55 µmol/L
7 years-20 years22-63 µmol/L
21 years or older25-60 µmol/L

 Carnitine, EsterifiedEffective February 18, 2014
AgeEsterified Carnitine
1-31 days4-29 µmol/L
32 days-12 months7-24 µmol/L
13 months-6 years4-36 µmol/L
7 years-20 years3-38 µmol/L
21 years or older5-29 µmol/L

 Carnitine, Esterified/Free RatioEffective February 18, 2014
AgeRatio Esterified/Free
1-31 days0.2- 0.8
32 days-12 months0.1- 0.8
13 months-6 years0.1- 0.8
7 years-20 years0.1- 0.9
21 years or older0.1-1.0

 By Report

Interpretive Data


Compliance Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
Note
The concentration of esterified carnitine is derived from a mathematical calculation using free and total carnitine.
CPT Code(s)
82017; 82379
Components
Component Test Code*Component Chart NameLOINC
0040029C5-OH, 3-OH Isovaleryl39001-3
0040034Acylcarnitine, Plasma Interpretation46252-3
0040037C2, Acetyl30191-1
0040038C3, Propionyl30551-6
0040039C4, Iso-/Butyryl35655-0
0040042C5, Isovaleryl/2Mebutyryl30531-8
0040046C5-DC, Glutaryl30349-5
0040047C6, Hexanoyl30358-6
0040049C8, Octanoyl30540-9
0040054C8:1, Octenoyl30541-7
0040057C10, Decanoyl30327-1
0040058C10:1, Decenoyl30328-9
0040062C12, Dodecanoyl30331-3
0040063C12:1, Dodecenoyl30332-1
0040064C12-OH, 3-OH-Dodecanoyl30233-1
0040066C14, Tetradecanoyl30565-6
0040067C14:1, Tetradecenoyl30566-4
0040068C14:2, Tetradecadienoyl30564-9
0040069C14-OH, 3-OH-Tetradecanoyl30238-0
0040074C14:1-OH, 3-OH-Tetradecenoyl30190-3
0040076C16, Palmitoyl30356-0
0040077C16:1, Palmitoleyl30357-8
0040078C16-OH, 3-OH-Palmitoyl30234-9
0040079C16:1-OH, 3-OH-Palmitoleyl30235-6
0040087C18, Stearoyl30560-7
0040093C18:1, Oleyl30542-5
0040094C18:2, Linoleyl30534-2
0040097C18-OH, 3-OH-Stearoyl35656-8
0040098C18:1-OH, 3-OH-Oleyl30312-3
0040101C18:2-OH, 3-OH-Linoleyl30237-2
0080066Carnitine, Free14286-9
0081108Carnitine, Total14288-5
0081291Carnitine, Esterified19074-4
0081292Carnitine Esterified/Free (Ratio)40869-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • carnitine panel, plasma
  • plasma carnitine panel