Maternal Serum Screening, Integrated, Specimen #2
Ordering Recommendation
Second part of a 2-part test. Requires that the first part (Maternal Serum Screening, Integrated, Specimen #1 0081062) was submitted in the first trimester. Screening test for DS, T18, and ONTD. Risks determined using a combination of 1st and 2nd trimester serum markers, with or without 1st trimester nuchal translucency (NT) measurement.
Quantitative Chemiluminescent Immunoassay
2-4 days  
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Requires a previously submitted first trimester specimen, Maternal Serum Screening, Integrated, Specimen #1 (ARUP test code 0081062).  Specimen must be drawn between 15 weeks, 0 days and 24 weeks, 6 days gestation.  
Serum separator tube or plain red.  
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 3 mL serum to an ARUP Standard Transport Tube. (Min: 1 mL)  
Storage/Transport Temperature
Unacceptable Conditions
Plasma. Specimens exposed to repeated freeze/thaw cycles. Hemolyzed specimens.  
The patient demographic information provided with the Integrated, Specimen #1 will be used to calculate the risks for this report. No new demographic information is required.  
After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 year  
Reference Interval
By report

Includes AFP, hCG, Estriol, Inhibin A, and previous PAPP-A.
Intervals are based upon weeks of gestation.  
Interpretive Data
Refer to report.  
CPT Code(s)
(82105; 84702;82677;86336) or 81511*

*The 2014 AMA CPT manual contains the component CPT Codes and the new MAAA codes.  Please direct any questions regarding CPT coding to the payer being billed.
Component Test Code*Component Chart Name
0080021Patient's AFP
0080241Estimated Due Date
0080267MoM for DIA
0080268Patient's DIA
0080917Maternal Weight
0080918MoM for AFP
0080920Maternal Screen Interpretation
0080924Insulin Req Maternal Diabetes
0080925Family Hx Neural Tube Defect
0080926Maternal Race
0080927Number of Fetuses
0080932Maternal Age At Delivery
0080935Patient's hCG
0080937MoM For hCG
0080938Gestational Age (Exact)
0080941Patient's uE3
0080943MoM for uE3
0081065Nuchal Translucency (NT)
0081066Crown Rump Length
0081067Patient's PAPP-A
0081068MoM for PAPP-A
0081069Sonographer Certification #
0081070Sonographer Name
0081071Ultrasound Date
0081074MoM for NT
0081158Family History of Aneuploidy
2002855EER Maternal Screening, INT-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • Second trimester screen