17-Ketosteroids, Urine
Ordering Recommendation

Assess adrenal androgen production. Preferred test is serum dehydroepiandrosterone sulfate (0070040).

Quantitative Spectrophotometry
Mon, Wed, Fri
1-5 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
24-hour urine. Refrigerate during collection.  
Specimen Preparation
Transfer two 4 mL aliquots from a well-mixed 24-hour urine collection into 2 ARUP Standard Transport Tubes or 2 ARUP Standard Transport Tubes containing 20 mg Sulfamic Acid (ARUP supply #48098) available online through eSupply using ARUP Connect or by contacting ARUP Client Services at (800) 522-2787. (Min: 3 mL/aliquot) Adequate refrigeration is the most important aspect of specimen preservation.  
Storage/Transport Temperature
Unacceptable Conditions
Record total volume and collection time interval on transport tube and test request form.  
Ambient: 4 hours; Refrigerated: 2 weeks; Frozen: 1 month  
Reference Interval
Test Number
Reference Interval
 17-Ketosteroids - per 24h
0-11 months: 0.0-1.0 mg/d
1-5 years: 1.0-2.0 mg/d
6-10 years: 1.0-4.4 mg/d
11-12 years: 1.3-8.5 mg/d
13-16 years: 3.4-9.8 mg/d
17-50 years: 5.3-17.6 mg/d
51 years and older: 4.1-12.1 mg/d
0-11 months: 0.0-1.0 mg/d
1-5 years: 1.0-2.0 mg/d
6-10 years: 1.4-3.9 mg/d
11-12 years: 3.8-9.5 mg/d
13-16 years: 4.5-17.1 mg/d
17-50 years: 4.4-14.2 mg/d
51 years and older: 3.2-10.6 mg/d

 17-Ketosteroids - per volumeNot available
 Creatinine, Urine - per 24h
3-8 years140-700 mg/d140-700 mg/d
9-12 years300-1300 mg/d300-1300 mg/d
13-17 years500-2300 mg/d400-1600 mg/d
18-50 years1000-2500 mg/d700-1600 mg/d
51-80 years800-2100 mg/d500-1400 mg/d
81 years and older600-2000 mg/d400-1300 mg/d

 Creatinine, Urine - per volumeNo reference interval

Interpretive Data
Reference intervals for random urine samples (mg/L) are not available.

An alternative and more specific test for adrenal androgen function is Dehydroepiandrosterone Sulfate, Serum (ARUP test code 0070040).

A large number of substances may interfere with this test. Decreases may be caused by carbamazepine, cephaloridine, cephalothin, chlormerodrin, digoxin, glucose, metyrapone, promazine, propoxyphene, reserpine, and others. Increases may be caused by acetone, acetophenide, ascorbic acid, chloramphenicol, chlorothiazide, chlorpromazine, cloxacillin, dexamethasone, erythromycin, ethinamate, etryptamine, methicillin, methyprylon, morphine, oleandomycin, oxacillin, penicillin, phenaglycodol, phenazopyridine, phenothiazine, piperidine, quinidine, secobarbital, spironolactone, and others. 
CPT Code(s)
Component Test Code*Component Chart NameLOINC
0020207Creatinine, Urine - per volume2161-8
0020208Creatinine, Urine - per 24h2162-6
008019017-Ketosteroids - per volume21038-5
008019117-Ketosteroids - per 24h6766-0
0097110Total Volume19153-6
0097111Hours Collected30211-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.