Vitamin A (Retinol), Serum or Plasma
0080525
 
Ordering Recommendation
Mnemonic
VIT A
Methodology
Quantitative High Performance Liquid Chromatography
Performed
Sun-Sat
Reported
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Patient should fast for 12 hours and abstain from alcohol for 24 hours prior to collection.  
Collect
Green (sodium or lithium heparin) or serum separator tube. Also acceptable: Lavender (EDTA) or pink (K2EDTA).  
Specimen Preparation
Protect from light during collection, storage, and shipment. Separate serum or plasma within 1 hour of collection. Transfer 1 mL serum or plasma to an ARUP Amber Transport Tube immediately. (Min: 0.2 mL) Avoid hemolysis.  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Whole blood or body fluids other than serum or plasma.  
Remarks
 
Stability
After separation from cells: Ambient: Unacceptable; Refrigerated: 1 month; Frozen: 1 year  
Reference Interval
Test Number Components Reference Interval
Vitamin A (Retinol)
Age Reference Interval
0-​1 month
2 months-​12 years
13-​17 years
18 years and older
0.18-​0.50 mg/L
0.20-​0.50 mg/L
0.26-​0.70 mg/L
0.30-​1.20 mg/L
Retinyl Palmitate 0-​150 years: 0-​0.10 mg/L
Interpretive Data


See Compliance Statement B: www.aruplab.com/CS
Note
Serum retinol is typically maintained until hepatic stores are almost depleted. Values greater than 0.30 mg/L represent adequate liver stores, whereas values less than 0.10 mg/L indicate deficiency. Samples that come in contact with plastic tubing or have been exposed to excessive light may show low results.

Vitamin A toxicity occurs when retinol concentration exceeds the capacity of retinol binding protein (RBP). Individuals with compromised renal function can retain RBP and may, therefore, have moderate retinol elevations. Drugs which interfere with vitamin A analysis include probucol (Lorelco).

This assay does not measure other vitamin A metabolites such as retinaldehyde and retinoic acid.
CPT Code(s)
84590
Components
Component Test Code*Component Chart Name
0080375Vitamin A (Retinol)
0080523Vitamin A, Ser/Pla - Interpretation
0080524Vitamin A (Retinyl Palmitate)
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at interface.support@aruplab.com.
Cross References
  • A Vitamin
  • Retinol
  • Retinyl palmitate