Vitamin B1 (Thiamine), Whole Blood
0080388
Ordering Recommendation
Do not use to monitor thiamine supplementation. Use to determine thiamine deficiency.
Mnemonic
VIT B1 WB
Methodology
Quantitative High Performance Liquid Chromatography
Performed
Sun-Sat
Reported
2-4 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Green (sodium or lithium heparin), lavender (EDTA), or pink (K2EDTA).  
Specimen Preparation
Protect from light within one hour of collection and during storage and shipment. Transfer 3 mL whole blood to an ARUP Amber Transport Tube. (Min: 0.6 mL)  
Storage/Transport Temperature
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.  
Unacceptable Conditions
Any specimen other than whole blood. Glass tubes. Clotted or non-frozen specimens.  
Remarks
  
Stability
Ambient: Unacceptable; Refrigerated: 4 hours; Frozen: 6 months  
Reference Interval
70-180 nmol/L  
Interpretive Data
This assay measures the concentration of thiamine diphosphate (TDP), the primary active form of vitamin B1. Approximately 90 percent of vitamin B1 present in whole blood is TDP. Thiamine and thiamine monophosphate, which comprise the remaining 10 percent, are not measured.

See Compliance Statement B: www.aruplab.com/CS
Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
 
Note
Whole blood is the preferred specimen for thiamine assessment.  Approximately 80 percent of thiamine present in whole blood is found in red blood cells. 
CPT Code(s)
84425
Components
Component Test Code*Component Chart NameLOINC
0080388Vitamin B1, Whole Blood2998-3
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Aliases
  • B1 Vitamin
  • TDP
  • Thiamin Pyrophosphate
  • Thiamine
  • Thiamine Diphosphate
  • TPP
  • VITB1