Vitamin C (Ascorbic Acid), Plasma
Ordering Recommendation

Use for nutritional assessment of vitamin C.

Quantitative High Performance Liquid Chromatography
Sun, Tue-Thu, Sat
1-6 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Green (sodium or lithium heparin). Place specimen in ice bath immediately. Also acceptable: Plasma separator tube. 
Specimen Preparation
Protect from light, centrifuge, transfer plasma and freeze within 1 hour of collection. Transfer 0.5 mL plasma to an ARUP Amber Transport Tube. (Min: 0.3 mL) 
Storage/Transport Temperature
CRITICAL FROZEN AND LIGHT PROTECTED. Separate specimens must be submitted when multiple tests are ordered 
Unacceptable Conditions
EDTA plasma, whole blood, or body fluids. Grossly hemolyzed specimens. 
Thawing and refreezing of the specimen and exposure to light will result in decreased Vitamin C concentration. 
After separation from cells: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 1 year 
Reference Interval
23-114 µmol/L
Interpretive Data
Vitamin C concentrations lower than 11 µmol/L indicate deficiency. Concentrations between 11 and 23 µmol/L are consistent with a moderate risk of deficiency due to inadequate tissue stores.

Vitamin C concentration is reported as micromoles per liter (µmol/L). To convert concentration to milligrams per deciliter (mg/dL), multiply the result by 0.0176.

Test developed and characteristics determined by ARUP Laboratories.

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Fasting specimen preferred. Thawing and refreezing of the specimen and exposure to light will result in decreased Vitamin C concentration.
Hotline History
Component Test Code*Component Chart NameLOINC
0080380Vitamin C, Plasma1903-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • Ascorbate