Pyridinoline and Deoxypyridinoline by HPLC
0080342
Ordering Recommendation
 
Mnemonic
PYD & DPD
Methodology
High Performance Liquid Chromatography
Performed
Wed
Reported
6-14 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
First morning void.  
Collect
Urine.  
Specimen Preparation
Transfer 8 mL urine to ARUP Standard Transport Tubes. (Min: 4 mL)  
Storage/Transport Temperature
Frozen.  
Unacceptable Conditions
Random urine.  
Remarks
  
Stability
Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 6 months  
Reference Interval
 
 
   

Age
PYR
µmol/mol creatinine
DPYR
µmol/mol creatinine

DPYR/PYR Ratio
0-​11 months 353-​560 µmol/mol crt 46-​113 µmol/mol crt 0.13-​0.20
1-​3 years 108-​400 µmol/mol crt 19-​94 µmol/mol crt 0.18-​0.24
4-​9 years 117-​325 µmol/mol crt 20-​75 µmol/mol crt 0.19-​0.25
10-​14 years 81-​267 µmol/mol crt 13-​61 µmol/mol crt 0.17-​0.27
15-​19 years 38-​80 µmol/mol crt 10-​18 µmol/mol crt 0.20-​0.26
20 years and older 20-​40 µmol/mol crt 5-​11 µmol/mol crt 0.23-​0.29
Interpretive Data
Pyridinoline and Deoxypyridinoline excretion follows a circadian rhythm. Reference intervals have been established on first morning void urine samples.

See Compliance Statement B: www.aruplab.com/CS
Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
 
Note
 
CPT Code(s)
82523
Components
Component Test Code*Component Chart NameLOINC
0020207Creatinine, Urine - per volume20624-3
0080343Pyridinoline25129-8
0080344Deoxypyridinoline25095-1
0080346DPYR/PYD Ratio58954-9
0080347PYD and DPD Interpretation 
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Deoxypyridinoline and Pyridinoline, HPLC