Pyridinoline and Deoxypyridinoline by HPLC
0080342
 
Ordering Recommendation
Mnemonic
PYD & DPD
Methodology
High Performance Liquid Chromatography
Performed
Wed
Reported
6-14 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
First morning void.  
Collect
Urine.  
Specimen Preparation
Transfer 8 mL urine to ARUP Standard Transport Tubes. (Min: 4 mL)  
Storage/Transport Temperature
Frozen.  
Unacceptable Conditions
Random urine.  
Remarks
 
Stability
Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 6 months  
Reference Interval

Age
PYR
µmol/mol creatinine
DPYR
µmol/mol creatinine

DPYR/PYR Ratio
0-​11 months 353-​560 µmol/mol crt 46-​113 µmol/mol crt 0.13-​0.20
1-​3 years 108-​400 µmol/mol crt 19-​94 µmol/mol crt 0.18-​0.24
4-​9 years 117-​325 µmol/mol crt 20-​75 µmol/mol crt 0.19-​0.25
10-​14 years 81-​267 µmol/mol crt 13-​61 µmol/mol crt 0.17-​0.27
15-​19 years 38-​80 µmol/mol crt 10-​18 µmol/mol crt 0.20-​0.26
20 years and older 20-​40 µmol/mol crt 5-​11 µmol/mol crt 0.23-​0.29
Interpretive Data
Pyridinoline and Deoxypyridinoline excretion follows a circadian rhythm. Reference intervals have been established on first morning void urine samples.

See Compliance Statement B: www.aruplab.com/CS
Note
CPT Code(s)
82523
Components
Component Test Code*Component Chart Name
0020207Creatinine, Urine - per volume
0080343Pyridinoline
0080344Deoxypyridinoline
0080346DPYR/PYD Ratio
0080347PYD and DPD Interpretation
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at interface.support@aruplab.com.
Cross References
  • Deoxypyridinoline and Pyridinoline, HPLC