Phenylalanine and Tyrosine
0080336
Ordering Recommendation
Use for monitoring patients with an established diagnosis of phenylketonuria (PKU).
Mnemonic
PHE/TYR
Methodology
Quantitative Liquid Chromatography/Tandem Mass Spectrometry
Performed
Mon-Fri
Reported
2-5 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Green (sodium or lithium heparin).  
Specimen Preparation
Transfer 0.5 mL plasma to an ARUP Standard Transport Tube. (Min: 0.25 mL)  
Storage/Transport Temperature
Frozen.  
Unacceptable Conditions
Hemolyzed specimens.  
Remarks
  
Stability
After separation from cells: Ambient: Unacceptable; Refrigerated: 24 hours; Frozen: 1 month  
Reference Interval
 
 
Test Number Components Reference Interval
0080315Phenylalanine Monitoring, Plasma Effective February 18, 2014
 
0-​30 days 30 -​ 100 µmol/L
1 month -​ 11 months 30 -​ 90 µmol/L
1 year and older 30 -​ 80 µmol/L
0080355Tyrosine, Plasma 0-​11 months: 30-​140 µmol/L
1 year and older: 30-​120 µmol/L
Interpretive Data


See Compliance Statement B: www.aruplab.com/CS
Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
 
Note
This test is designed to monitor treatment and compliance in PKU patients.
CPT Code(s)
82131; 84510
Components
Component Test Code*Component Chart NameLOINC
0080315Phenylalanine, Plasma14875-9
0080355Tyrosine, Plasma20660-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • PKU
  • Tyrosine