Pyruvic Acid, CSF
Ordering Recommendation
Useful for investigating possible disorders of mitochondrial metabolism, particularly when used in conjunction with CSF lactate.
New York DOH Approval Status
Specimen Required
Patient should be at complete rest.
CSF.
1) Immediately after CSF is drawn, add exactly 1 mL CSF to a chilled pyruvate collection tube containing 2 mL 8 percent (w/v) perchloric acid (ARUP supply #16567) available online through eSupply using ARUP Connect™ or contact Client Services at (800) 522-2787.
2) Mix well for 30 seconds then place in an ice bath for 10 minutes.
3) Centrifuge for 10 minutes at 1500 x g.
4) Decant 2 mL supernatant to an ARUP Standard Transport Tube and freeze. (Min: 1 mL)
Frozen.
If less than 1 mL of CSF is added to collection tube, pH of the supernatant will be too low for testing.
Ambient: Unacceptable; Refrigerated: 2 days; Frozen: 1 month
Methodology
Quantitative Enzymatic Assay
Performed
Sun-Sat
Reported
1-2 days
Reference Interval
0.060-0.190 mmol/L
Interpretive Data
Standard
Note
Hotline History
CPT Codes
84210
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0080312 | Pyruvic Acid, CSF | 14122-6 |
Aliases
- Pyruvate (Pyruvic Acid, CSF)
- Pyruvic Acid