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Porphobilinogen (PBG), Urine
0080260
Ordering Recommendation

Essential first-line test for suspected acute porphyria in adults. Use in determining metabolic response to IV hematin.

Mnemonic
PBGQT
Methodology
Quantitative Ion Exchange Chromatography/Spectrophotometry
Performed
Mon-Fri
Reported
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Random or 24-hour urine. Refrigerate 24-hour specimens during collection. 
Specimen Preparation
Protect from light. Transfer 8 mL aliquot from a random or well-mixed 24-hour collection to ARUP Amber Transport Tubes. (Min: 3.5 mL) Record total volume and collection time interval on transport tube and test request form. 
Storage/Transport Temperature
Frozen. 
Unacceptable Conditions
Body fluids other than urine. 
Remarks
 
Stability
Ambient: Unacceptable; Refrigerated: 4 days; Frozen: 1 month 
Reference Interval
Test Number
Components
Reference Interval
 Porphobilinogen (PBG), Urine -per volume0.0-8.8 µmol/L
 Porphobilinogen, Urine - per 24h0.0-11.0 µmol/d
0020473Creatinine, Urine - per 24h
Age
Male
Female
3-8 years140-700 mg/d140-700 mg/d
9-12 years300-1300 mg/d300-1300 mg/d
13-17 years500-2300 mg/d400-1600 mg/d
18-50 years1000-2500 mg/d700-1600 mg/d
51-80 years800-2100 mg/d500-1400 mg/d
81 years and older600-2000 mg/d400-1300 mg/d


Interpretive Data


Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
Appropriate test to rule out acute intermittent porphyria (AIP) and other acute attack types of porphyrias associated with neurologic and/or psychiatric symptoms.
Hotline History
N/A
Components
Component Test Code*Component Chart NameLOINC
0020207Creatinine, Urine - per volume2161-8
0020208Creatinine, Urine - per 24h2162-6
0080261Porphobilinogen, Urine - per 24h14882-5
0080262Porphobilinogen (PBG), Urine -per volume2811-8
0097110Total Volume19153-6
0097111Hours Collected30211-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • PBG, Quantitative
  • Porphobilinogen
  • Watson-Schwartz Test