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Porphobilinogen (PBG), Urine
0080260
Ordering Recommendation

Essential first-line test for suspected acute porphyria in adults. Use in determining metabolic response to IV hematin in adults.

Mnemonic
PBGQT
Methodology
Quantitative Ion Exchange Chromatography/Spectrophotometry
Performed
Mon-Fri
Reported
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Random or 24-hour urine. Refrigerate 24-hour specimens during collection.  
Specimen Preparation
Protect from light. Transfer 8 mL aliquot from a random or well-mixed 24-hour collection to ARUP Amber Transport Tubes. (Min: 3.5 mL) Record total volume and collection time interval on transport tube and test request form.  
Storage/Transport Temperature
Frozen.  
Unacceptable Conditions
Body fluids other than urine.  
Remarks
 
Stability
Ambient: Unacceptable; Refrigerated: 4 days; Frozen: 1 month  
Reference Interval
Test Number
Components
Reference Interval
 Porphobilinogen (PBG), Urine -per volume0.0-8.8 µmol/L
 Porphobilinogen, Urine - per 24h0.0-11.0 µmol/d
0020473Creatinine, 24-Hour Urine
Age
Male
Female
3-8 years140-700 mg/d140-700 mg/d
9-12 years300-1300 mg/d300-1300 mg/d
13-17 years500-2300 mg/d400-1600 mg/d
18-50 years1000-2500 mg/d700-1600 mg/d
51-80 years800-2100 mg/d500-1400 mg/d
81 years and older600-2000 mg/d400-1300 mg/d


Interpretive Data


Note
Appropriate test to rule out acute intermittent porphyria (AIP) and other acute attack types of porphyrias associated with neurologic and/or psychiatric symptoms.
CPT Code(s)
84110
Components
Component Test Code*Component Chart NameLOINC
0020207Creatinine, Urine - per volume2161-8
0020208Creatinine, Urine - per 24h2162-6
0080261Porphobilinogen, Urine - per 24h14882-5
0080262Porphobilinogen (PBG), Urine -per volume2811-8
0097110Total Volume19153-6
0097111Hours Collected30211-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • PBG, Quantitative
  • Porphobilinogen
  • Watson-Schwartz Test