Porphobilinogen (PBG), Urine
0080260
Ordering Recommendation
Essential first-line test for suspected acute porphyria in adults. Use in determining metabolic response to IV hematin.
Mnemonic
PBGQT
Methodology
Quantitative Ion Exchange Chromatography/Spectrophotometry
Performed
Mon-Fri
Reported
1-4 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Random or 24-hour urine. Refrigerate 24-hour specimens during collection.  
Specimen Preparation
Protect from light. Transfer 8 mL aliquot from a random or well-mixed 24-hour collection to ARUP Amber Transport Tubes. (Min: 3.5 mL) Record total volume and collection time interval on transport tube and test request form.  
Storage/Transport Temperature
Frozen.  
Unacceptable Conditions
Body fluids other than urine.  
Remarks
  
Stability
Ambient: Unacceptable; Refrigerated: 4 days; Frozen: 1 month  
Reference Interval
 
 
Test Number Components Reference Interval
 Porphobilinogen, Urine0.0-​8.8 µmol/L
 Porphobilinogen, Urine (24-​hour) 0.0-​11.0 µmol/d
0020473Creatinine, 24-​Hour Urine  
 
Age Male Female
3-​8 years 140-​700 mg/d 140-​700 mg/d
9-​12 years 300-​1300 mg/d 300-​1300 mg/d
13-​17 years 500-​2300 mg/d 400-​1600 mg/d
18-​50 years 1000-​2500 mg/d 700-​1600 mg/d
51-​80 years 800-​2100 mg/d 500-​1400 mg/d
81 years and older 600-​2000 mg/d 400-​1300 mg/d
Interpretive Data
 
Note
Appropriate test to rule out acute intermittent porphyria (AIP) and other acute attack types of porphyrias associated with neurologic and/or psychiatric symptoms.
CPT Code(s)
84110
Components
Component Test Code*Component Chart NameLOINC
0020207Creatinine, Urine - per volume20624-3
0020208Creatinine, Urine - per 24h2162-6
0080261Porphobilinogen, Urine - per 24h14882-5
0080262Porphobilinogen (PBG), Urine -per volume2811-8
0097110Total Volume19153-6
0097111Hours Collected30211-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • PBG, Quantitative
  • Porphobilinogen
  • Watson-Schwartz Test