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Amino Acids Quantitative by LC-MS/MS, CSF
0080137
Ordering Recommendation
 
Mnemonic
CSFAA QNT
Methodology
Quantitative Liquid Chromatography/Tandem Mass Spectrometry
Performed
Mon-Fri
Reported
2-5 days  
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
  
Collect
CSF.  
Specimen Preparation
Centrifuge CSF to separate and remove cellular material. Freeze supernatant. Transport 0.5 mL CSF. (Min: 0.3 mL)  
Storage/Transport Temperature
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.  
Unacceptable Conditions
  
Remarks
Clinical information is needed for appropriate interpretation. Additional required information includes age, gender, diet (e.g., TPN therapy), drug therapy, and family history. Biochemical Genetics Patient History Form is available on the ARUP Web site at http://www.aruplab.com/patienthistory or by contacting ARUP Client Services.  
Stability
Ambient: Unacceptable; Refrigerated: 24 hours; Frozen: 1 month  
Reference Interval
Effective May 18, 2015
 
Components Reference Interval Components Reference Interval
Alpha-​Aminoadipic acid 0.0 -​ 2.0 µmol/L Histidine 5.0 -​ 24.0 µmol/L
Alpha-​Amino-​n-​butyric acid 0.0 -​ 6.5 µmol/L Homocitrulline 0.0 -​ 4.0 µmol/L
Alanine 12.5 -​ 47.3 µmol/L Homocystine 0.0 -​ 2.0 µmol/L
Alloisoleucine 0.0 -​ 2.0 µmol/L Hydroxylysine 0.0 -​ 5.0 µmol/L
Anserine 0.0 -​ 7.0 µmol/L Hydroxyproline 0.0 -​ 8.0 µmol/L
Arginine 5.9 -​ 30.6 µmol/L Isoleucine 1.0 -​ 11.0 µmol/L
Argininosuccinic acid 0.0 -​ 2.0 µmol/L Leucine 3.4 -​ 25.9 µmol/L
Asparagine 0.0 -​ 23.6 µmol/L Lysine 7.8 -​ 40.8 µmol/L
Aspartic acid 0.0 -​ 5.8 µmol/L Methionine 0.0 -​ 10.0 µmol/L
Beta-​Alanine 2.7 -​ 21.7 µmol/L Ornithine 2.0 -​ 12.0 µmol/L
Beta-​Aminoisobutyric acid 0.0 -​ 2.0 µmol/L Phenylalanine 6.9 -​ 25.1 µmol/L
Citrulline 0.0 -​ 5.6 µmol/L Proline 0.0 -​ 8.0 µmol/L
Cystathionine 0.0 -​ 3.0 µmol/L Sarcosine 0.0 -​ 2.0 µmol/L
Cystine 0.0 -​ 5.0 µmol/L Serine 18.0 -​ 73.0 µmol/L
Ethanolamine 3.8 -​ 29.0 µmol/L Taurine 2.7 -​ 16.2 µmol/L
Gamma-​Amino-​n-​butyric acid 0.0 -​ 2.0 µmol/L Threonine 10.0 -​ 60.0 µmol/L
Glutamic acid 0.0 -​ 15.0 µmol/L Tryptophan 0.0 -​ 6.0 µmol/L
Glutamine 230.7 -​ 637.4 µmol/L Tyrosine 5.4 -​ 23.7 µmol/L
Glycine 3.1 -​ 21.0 µmol/L Valine 7.0 -​ 37.1 µmol/L
Interpretive Data


See Compliance Statement B: www.aruplab.com/CS
Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
 
Note
 
CPT Code(s)
82139
Components
Component Test Code*Component Chart NameLOINC
0080138Alanine, CSF22657-1
0080139Arginine, CSF22656-3
0080141Asparagine, CSF26603-1
0080142Aspartic Acid, CSF22655-5
0080143Citrulline, CSF22654-8
0080144Cystine, CSF22653-0
0080148Glutamine, CSF22641-5
0080149Glutamic Acid, CSF22652-2
0080151Glycine, CSF22650-6
0080152Histidine, CSF9453-2
0080153Homocystine, CSF22660-5
0080154Hydroxyproline, CSF26596-7
0080156Isoleucine, CSF22659-7
0080157Leucine, CSF9412-8
0080158Lysine, CSF22651-4
0080159Methionine, CSF22648-0
0080161Ornithine, CSF22647-2
0080162Phenylalanine, CSF22646-4
0080163Proline, CSF22645-6
0080167Serine, CSF22644-9
0080168Taurine, CSF26614-8
0080169Threonine, CSF22643-1
0080171Tyrosine, CSF22642-3
0080172Valine, CSF22649-8
0080173Amino Acids, CSF Interpretation48767-8
2011976Homocitrulline, CSF55875-9
2011977Hydroxylysine, CSF26595-9
2011983Sarcosine, CSF26598-3
2011984Tryptophan, CSF26602-3
2011985Alpha-amino butyric acid, CSF26586-8
2011986Allo-isoleucine, CSF22658-9
2011987Alpha-aminoadipic acid, CSF26587-6
2011988Anserine, CSF26588-4
2011989Argininosuccinic Acid, CSF40838-5
2011990Beta-alanine, CSF26589-2
2011991Beta-amino isobutyric acid, CSF26590-0
2011992Cystathionine, CSF26592-6
2011993Ethanolamine, CSF26593-4
2011994Gamma-amino butyric acid, CSF26594-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • CSF amino acids
  • quantitative analysis of amino acids