Aminolevulinic Acid (ALA), Urine
Ordering Recommendation
Evaluate suspected aminolevulinic acid dehydratase deficiency (ADP) porphyria, or hereditary tyrosinemia.
Quantitative Ion Exchange Chromatography/Spectrophotometry
Mon, Wed, Fri
1-4 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
Refrain from alcohol consumption 24 hours prior to collection.  
24 hour or random urine. Refrigerate 24-hour specimens during collection.  
Specimen Preparation
Protect from light. Transfer a 4 mL aliquot from a well-mixed 24 hour or random collection to an ARUP Amber Transport Tube. (Min: 1.2 mL) Record total volume and collection time interval on transport tube and test request form.  
Storage/Transport Temperature
Unacceptable Conditions
Body fluids other than urine.  
Ambient: Unacceptable; Refrigerated: 4 days; Frozen: 1 month  
Reference Interval
Test Number Components Reference Interval
 Aminolevulinic Acid, Urine0-​35 µmol/L
 Aminolevulinic Acid, Urine 0-​60 µmol/d
0020473Creatinine, 24-​Hour Urine  
Age Male Female
3-​8 years 140-​700 mg/d 140-​700 mg/d
9-​12 years 300-​1300 mg/d 300-​1300 mg/d
13-​17 years 500-​2300 mg/d 400-​1600 mg/d
18-​50 years 1000-​2500 mg/d 700-​1600 mg/d
51-​80 years 800-​2100 mg/d 500-​1400 mg/d
81 years and older 600-​2000 mg/d 400-​1300 mg/d
Interpretive Data
Increased ALA concentration is associated with exposure to alcohol, lead, and a variety of other agents.  Massive elevation of ALA occurs in the acute porphyrias and hereditary tyrosinemia.

Specimen preservation with acid or base is discouraged and may cause assay interference.  When collecting urine for additional tests that require acid or base preservation, the ALA aliquot should be removed prior to the addition of the acid or base.
CPT Code(s)
Component Test Code*Component Chart NameLOINC
0020207Creatinine, Urine - per volume2161-8
0020208Creatinine, Urine - per 24h2162-6
0080104Aminolevulinic Acid - per volume25896-2
0080105Aminolevulinic Acid - per 24h14689-4
0097110Total Volume19153-6
0097111Hours Collected30211-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • 5-Aminolevulinic Acid
  • ALA
  • Delta-ALA
  • Delta-Aminolevulinic Acid