Feedback
Carnitine, Free & Total (Includes Carnitine, Esterified)
0080068
Ordering Recommendation
Useful in the diagnosis of primary carnitine deficiency (carnitine uptake defect).
Monitor carnitine status.
Mnemonic
CARN F&T
Methodology
Tandem Mass Spectrometry
Performed
Tue-Sat
Reported
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Green (sodium or lithium heparin). Also acceptable: Plain red.  
Specimen Preparation
Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum or plasma to an ARUP Standard Transport Tube and freeze immediately. (Min: 0.2 mL) Avoid hemolysis.  
Storage/Transport Temperature
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.  
Unacceptable Conditions
Room temperature specimens. Specimens refrigerated greater than 12 hours.  
Remarks
 
Stability
After separation from cells: Ambient: Unacceptable; Refrigerated: 12 hours; Frozen: 1 month (avoid repeated freeze/thaw cycles)  
Reference Interval
AgeFree CarnitineTotal CarnitineEsterified CarnitineRatio Esterified: Free
1 - 31 days15 - 55 µmol/L21 - 83 µmol/L4 - 29 µmol/L0.2 - 0.8
32 days-12 months29 - 61 µmol/L38 - 73 µmol/L7 - 24 µmol/L0.1 - 0.8
13 months - 6 years25 - 55 µmol/L35 - 90 µmol/L4 - 36 µmol/L0.1 - 0.8
7 years -20 years22 - 63 µmol/L31 - 78 µmol/L3 - 38 µmol/L0.1 - 0.9
21 years or older25 - 60 µmol/L34 - 86 µmol/L5 - 29 µmol/L0.1 - 1.0

Interpretive Data


Compliance Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
Note
The concentration of esterified carnitine is derived from a mathematical calculation using free and total carnitine.
CPT Code(s)
82379
Components
Component Test Code*Component Chart NameLOINC
0080064Carnitine, Esterified14282-8
0080066Carnitine, Free14286-9
0080067Carnitine, Total14288-5
0081148Carnitine Esterified/Free (Ratio)40869-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Esterified carnitine
  • Free and Total Carnitine
  • L-Carnitine Free and Total