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IGF-1 (Insulin-Like Growth Factor 1)
0070125
Ordering Recommendation

Aids in diagnosis of growth hormone excess or deficiency disorders.

Mnemonic
IGF-1
Methodology
Quantitative Chemiluminescent Immunoassay
Performed
Sun-Sat
Reported
1-2 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Serum separator tube.  
Specimen Preparation
Transport 1 mL serum. (Min: 0.5 mL)  
Storage/Transport Temperature
Frozen.  
Unacceptable Conditions
Plasma, tissue, or urine. Grossly hemolyzed or lipemic specimens.  
Remarks
 
Stability
After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 year  
Reference Interval
Age
Female
Male
1-2 years
3 years
4 years
5 years
6 years
7 years
8-18 years
19-20 years
21-30 years
31-40 years
41-50 years
51-60 years
61-70 years
71-80 years
56-144 ng/mL
26-162 ng/mL
32-179 ng/mL
39-198 ng/mL
55-238 ng/mL
55-268 ng/mL
Refer to Tanner Stages
217-475 ng/mL
87-368 ng/mL
106-368 ng/mL
118-298 ng/mL
53-287 ng/mL
75-263 ng/mL
54-205 ng/mL
30-122 ng/mL
20-141 ng/mL
25-157 ng/mL
30-174 ng/mL
37-192 ng/mL
44-211 ng/mL
Refer to Tanner Stages
281-510 ng/mL
155-432 ng/mL
132-333 ng/mL
121-237 ng/mL
68-245 ng/mL
60-220 ng/mL
36-215 ng/mL

Female Tanner Stages
I (8-12 yrs)64-358 ng/mL
II (8-14 yrs)89-566 ng/mL
III (9-15 yrs)192-568 ng/mL
IV & V (11-18 yrs)147-646 ng/mL
Male Tanner Stages
I (8-15 yrs)52-391 ng/mL
II & III (8-16 yrs)39-648 ng/mL
IV & V (11-18 yrs)144-673 ng/mL

Interpretive Data
IGF-1 values well above the age and gender matched reference interval indicate a possible pituitary tumor secreting growth hormone. IGF-1 values below the reference interval indicate a possible GH deficiency.


Note
CPT Code(s)
84305
Components
Component Test Code*Component Chart NameLOINC
0070125IGF-1 (Insulin-Like Growth I)2484-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • IGF
  • IGF-1
  • IGF1
  • Insulin-Like Growth Factor 1, Serum
  • Insulin-Like Growth Factor I
  • Somatomedin C