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Growth Hormone, 0 Minutes
0070081
Ordering Recommendation
Mnemonic
GH 0
Methodology
Quantitative Chemiluminescent Immunoassay
Performed
Sun-Sat
Reported
1-2 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Plasma separator tube or serum separator tube. Collect one tube per timed specimen. Also acceptable: Green (sodium or lithium heparin) or lavender (EDTA), or pink (K2EDTA). 
Specimen Preparation
Allow specimen to clot completely at room temperature.  Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma per timed specimen to individual ARUP Standard Transport Tubes. (Min: 0.4 mL per timed specimen) 
Storage/Transport Temperature
Frozen. Also acceptable: Refrigerated. 
Unacceptable Conditions
Tissue or urine. Grossly hemolyzed or lipemic specimens. 
Remarks
 
Stability
After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 2 months 
Reference Interval
Effective May 20, 2013
Age
Male
Female
0-6 years0.10-6.20 ng/mL0.10-6.20 ng/mL
7-17 years0.05-11.00 ng/mL0.05-17.30 ng/mL
18 years and older0.05-3.00 ng/mL0.05-8.00 ng/mL

Interpretive Data
Growth hormone stimulation tests should induce a peak of greater than 5 ng/mL in children and greater than 4 ng/mL in adults; lower values suggest growth hormone deficiency. For children, some experts consider values of 5-8 ng/mL equivocal and only peak values of greater than 8 ng/mL as truly normal.

For suppression testing, normal subjects have growth hormone concentrations of less than 0.8 ng/mL within 2 hours of ingestion of a 75 or 100 gram glucose dose. Patients with acromegaly fail to show normal suppression.

Note
This Growth Hormone assay is now standardized to the Recombinant Second International Standard (IS): 98/574. Growth hormone results read approximately 25 percent lower than with the previous standards (First IS: 80/505). Reference ranges have also been modified according to the assay manufacturer.
CPT Code(s)
83003
Components
Component Test Code*Component Chart NameLOINC
0070081Growth Hormone 0 Minutes12253-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • GH
  • GH testing
  • GHRH
  • Growth Hormone Provocative Test
  • Growth Hormone Stimulation
  • growth hormone, Serum
  • hGH
  • Human Growth Hormone
  • Somatotrophic Hormone
  • Somatotropin