Histamine, Urine
Ordering Recommendation

Aid in evaluation of patient with allergic signs and symptoms, such as anaphylaxis. May assist when diagnosing and monitoring mast-cell activation disorders or when evaluating histamine production over a longer time frame.

Quantitative Enzyme Immunoassay
Tue, Sat
1-6 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Random or 24-hour urine in a plastic container. Refrigerate during collection. 
Specimen Preparation
Transfer a 4 mL aliquot from a well-mixed random or 24-hour collection to an ARUP Standard Transport Tube and freeze immediately. (Min: 1 mL) Record total volume and collection time interval on transport tube and test request form. 
Storage/Transport Temperature
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered. 
Unacceptable Conditions
Ambient: Unacceptable; Refrigerated: 6 hours; Frozen: 6 months 
Reference Interval
Effective February 21, 2012
ComponentsReference Interval
Histamine, Urine - ratio to CRT0-450 nmol/g crt
Histamine, Urine, Excretion - 24h0-60 µg/day

Interpretive Data

Compliance Statement D: For laboratory tests using a manufactured RUO kit. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

If 24-hour urine is submitted, the excretion will be calculated. If random urine is submitted, the result will be reported as Not applicable.
Hotline History
View Hotline History
Component Test Code*Component Chart NameLOINC
0020207Creatinine, Urine - per volume2161-8
0070039Histamine, Urine - per volume33290-8
0070041Histamine, Urine - ratio to CRT25925-9
0097110Total Volume19153-6
0097111Hours Collected30211-7
2005776Histamine, Urine, Excretion - 24 h9410-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • urine histamine