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Cortisol, Serum
0070030
Ordering Recommendation

• Differential diagnosis of Cushing syndrome.
• Screen and diagnose primary and secondary adrenal insufficiency.

Mnemonic
CORTISOL
Methodology
Quantitative Chemiluminescent Immunoassay
Performed
Sun-Sat
Reported
Within 24 hours
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Serum separator tube (SST).    
Specimen Preparation
Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube.(Min: 0.6 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Saliva (refer to Cortisol, Saliva, ARUP test code 0081117).  
Remarks
 
Stability
After separation from cells: Ambient: 1 week; Refrigerated: 1 week; Frozen: 3 months  
Reference Interval
Interpretive Data
0800 hours: 6.0-23.0 µg/dL
2000 hours: 0.0-9.0 µg/dL
8 hours post 1 mg dexamethasone given at midnight: 0.0-5.0µg/dL
30-60 minutes post 25 units Cosyntropin I.V.:>20.0µg/dL


Note
To convert to nmol/L, multiply µg/dL by 27.6.
CPT Code(s)
82533
Components
Component Test Code*Component Chart NameLOINC
0070030Cortisol, Serum2143-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Compound F
  • Corticosteroids
  • Cortisol
  • Cortisol, Serum
  • Cortrosyn Stimulation Test
  • Dexamethasone Suppression
  • Diurnal Corticoids