Parvovirus B 19 Antibody, IgM
0065122
Ordering Recommendation
Submit With Order
Mnemonic
PARVO M
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Sun-Sat
Reported
1-3 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
 
Collect
Serum separator tube. Also acceptable: Lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).  
Specimen Preparation
Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.3 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent."  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Contaminated, heat-inactivated, hemolyzed, hyperlipemic, or icteric serum.  
Remarks
 
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)  
Reference Interval
0.89 IV or less: Negative - No significant level of detectable Parvovirus B19 IgM antibody.
0.90-1.10 IV: Equivocal - Repeat testing in 10-14 days may be helpful.
1.11 IV or greater: Positive - IgM antibody to Parvovirus B19 detected, which may indicate a current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.
Interpretive Data
The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.

Appearance of an IgM antibody response normally occurs 7 to 14 days after the onset of disease. Testing immediately post-exposure is of no value without a later convalescent specimen. A residual IgM response may be distinguished from early IgM response to infection by testing sera from patients three to four weeks later for changing levels of specific IgM antibodies.
Note
CPT Code(s)
86747
Components
Component Test Code*Component Chart Name
0065122Parvovirus B19 Antibody IgM
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Cross References
  • B19
  • B19 IgM Antibodies
  • Erythrovirus B19 IgM
  • Human Parvovirus B19 IgM