Parvovirus B19 Antibodies Seroconversion, IgG and IgM
0065109
 
Ordering Recommendation
Mnemonic
PARVO SERO
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Sun-Sat
Reported
1-3 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
 
Collect
Serum separator tube (acute) AND serum separator tube (convalescent). Also acceptable: Lavender (EDTA) or green (sodium or lithium heparin).  
Specimen Preparation
Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum or plasma (acute) AND 0.5 mL serum or plasma (convalescent) to individual ARUP Standard Transport Tubes. (Min: 0.3 mL each) If acute specimen was previously tested by ARUP, convalescent specimen must be submitted within 30 days if seroconversion comparison testing is desired. Mark specimens plainly as "acute" or "convalescent" with appropriate draw dates.  
Storage/Transport Temperature
Refrigerated..  
Unacceptable Conditions
Contaminated, heat-inactivated, hemolyzed, icteric, or severely lipemic specimens.  
Remarks
Testing will not be performed unless both acute and convalescent specimens are available.  
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 5 days; Frozen: 1 year (avoid repeated freeze/thaw cycles)  
Reference Interval
Test Number Components Reference Interval
Parvovirus B19 Antibody, IgG Acute 0.89 IV or less: Negative -​ No significant level of detectable Parvovirus B19 IgG antibody.
0.90-​1.10 IV: Equivocal -​ Repeat testing in 10-​14 days may be helpful.
1.11 IV or greater: Positive -​ IgG antibody to Parvovirus B19 detected which may indicate a current or past infection.
Parvovirus B19 Antibody, IgG Convalescent 0.89 IV or less: Negative -​ No significant level of detectable Parvovirus B19 IgG antibody.
0.90-​1.10 IV: Equivocal -​ Repeat testing in 10-​14 days may be helpful.
1.11 IV or greater: Positive -​ IgG antibody to Parvovirus B19 detected which may indicate a current or past infection.
Parvovirus B19 Antibody, IgM Acute 0.89 IV or less: Negative -​ No significant level of detectable Parvovirus B19 IgM antibody.
0.90-​1.10 IV: Equivocal -​ Repeat testing in 10-​14 days may be helpful.
1.11 IV or greater: Positive -​ IgM antibody to Parvovirus B19 detected which may indicate a current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-​infection.
Parvovirus B19 Antibody, IgM Convalescent 0.89 IV or less: Negative -​ No significant level of detectable Parvovirus B19 IgM antibody.
0.90-​1.10 IV: Equivocal -​ Repeat testing in 10-​14 days may be helpful.
1.11 IV or greater: Positive -​ IgM antibody to Parvovirus B19 detected which may indicate a current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-​infection.
Interpretive Data
Note
CPT Code(s)
86747 x4
Components
Component Test Code*Component Chart Name
0065133Parvovirus B19 Antibody, IgG Acute
0065134Parvovirus B19 Ab, IgG Convalescent
0065135Parvovirus B19 Antibody, IgM Acute
0065136Parvovirus B19 Ab, IgM Convalescent
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at interface.support@aruplab.com.
Cross References
  • B19
  • B19 Antibodies Seroconversion
  • Erythrovirus B19
  • Fifth Disease
  • Human Parvovirus B19 Antibodies Seroconversion