Varicella-Zoster Virus DFA
0060290
Ordering Recommendation
 
Mnemonic
VZVFA
Methodology
Direct Fluorescent Antibody Stain
Performed
Sun-Sat
Reported
Within 24 hours  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
Collect vesicle specimen during first 3 days of rash.  
Collect
Vesicle swab, tissue, or skin scrapings. Swab should be rolled in base of fresh vesicle to obtain cells.  
Specimen Preparation
Immediately transfer specimen to viral transport media (ARUP Supply #12884) and refrigerate (extremely temperature sensitive).  Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787.  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Bone marrow, CSF, or whole blood. Calcium alginate, eSwab, dry or wood swabs.  
Remarks
Specimen source preferred.  
Stability
Ambient: 4 hours; Refrigerated: 72 hours; Frozen: Unacceptable  
Reference Interval
Negative  
Interpretive Data
Approximately 20% of samples submitted for VZV are positive for herpes simplex virus. Testing for herpes simplex virus is NOT included in this test.  
Note
Sensitivity of DFA methodology is dependent upon adequacy of the specimen.  If there are fewer than 20 cells, the DFA result will be reported as "sample inadequate."

Culture is recommended for any DFA-negative swabs or inadequate samples. Refer to Varicella-Zoster Virus DFA with Reflex to Varicella-Zoster Virus Culture (0060282).
CPT Code(s)
87290
Components
Component Test Code*Component Chart NameLOINC
0060290Varicella-Zoster Virus by DFA5882-6
0060341Varicella-Zoster Virus FA Source31208-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Herpes Zoster Virus
  • Varicella Zoster Virus
  • VZV
  • VZV Antigen Detection