Varicella-Zoster Virus DFA with Reflex to Varicella-Zoster Virus Culture
0060282
Ordering Recommendation
 
Mnemonic
VZVFAC
Methodology
Direct Fluorescent Antibody Stain/Cell Culture
Performed
Sun-Sat
Reported
3-5 days
DFA: Within 24 hours; Culture: 3-5 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
Collect vesicle specimen during first three days of rash.  
Collect
Vesicle fluid or swab, tissue, or skin scrapings. Swab should be rolled in base of fresh vesicle to obtain cells.  
Specimen Preparation
Immediately transfer specimen to viral transport media (ARUP Supply #12884) and refrigerate (extremely temperature sensitive). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787.  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Bone marrow CSF, or whole blood. Calcium alginate, eSwab, dry or wood swabs.  
Remarks
Specimen source preferred.  
Stability
Ambient: Unacceptable; Refrigerated: 48 hours; Frozen: Unacceptable  
Reference Interval
Negative  
Interpretive Data
Approximately 20% of samples submitted for VZV are positive for herpes simplex virus. Testing for herpes simplex virus is NOT included in this test.  
Note
If DFA is negative or inadequate, then a VZV culture will be added. Additional charges apply.

Sensitivity of DFA methodology is dependent upon adequacy of the specimen. If specimen contains fewer than 20 cells, then the DFA result will be reported as "inadequate."
CPT Code(s)
87290; if reflexed, add 87252; 87254
Components
Component Test Code*Component Chart NameLOINC
0060282Varicella-Zoster Virus, DFA5882-6
0060335Varicella-Zoster Virus Fac Source 
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Aliases
  • Herpes Zoster
  • Herpes Zoster Antigen Detection & Culture
  • Varicella Zoster Virus
  • Varicella Zoster Virus Antigen Detection
  • VZV
  • VZV DFA