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Antimicrobial Susceptibility - Mould  Susceptibility (INACTIVE as of 02/18/14. Refer to 2009257)
0060227
Ordering Recommendation
Mnemonic
MA MOULD
Methodology
Broth Microdilution
Performed
Sun-Sat
Reported
3-12 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Actively growing mould in pure culture. 
Specimen Preparation
Transport sealed container with pure culture on fungal medium slant.  Place each specimen in an individually sealed bag. 
Storage/Transport Temperature
Room temperature. 
Unacceptable Conditions
Mixed cultures or non-viable moulds. Agar plates. 
Remarks
Isolate identification and specimen source required. 
Stability
Ambient: 2 weeks; Refrigerated: 2 weeks; Frozen: Unacceptable 
Reference Interval
Minimum inhibitory concentration (MIC) without interpretation.
Minimum effective concentrations (MEC) without interpretation for the echinocandins.
Interpretive Data
Interpretive MIC breakpoints have not been established for mould. Experience to date indicates that amphotericin B MICs for most opportunistic mould isolates cluster between 0.5-2.0 µg/mL. However, for some species (eg, A. terreus) the MIC may range between 2-16 µg/mL. Filamentous fungi are usually not susceptible to 5-fluorocytosine or fluconazole and therefore are not reported. The echinocandins do not have activity against Fusarium species and therefore are not reported.

Susceptibility testing is performed by CLSI-approved broth microdilution method

Note
The following antifungal agents are tested: Amphotericin B, anidulafungin, caspofungin, fluconazole, 5-fluorocytosine, griseofulvin, itraconazole, micafungin, posaconazole, terbinafine, and voriconazole. Selective reporting by organism.

Susceptibility testing for dermatophytes and dimorphic fungi is not performed at ARUP. If requested, isolates will be sent to the Fungus Testing Laboratory, San Antonio, TX. Specify agents to be tested on the susceptibility test requisition form.
 
An additional processing fee will be billed for all organisms not submitted in pure culture per specimen requirements.

If species identification is not provided, identification will be performed at ARUP. Additional charges apply.

Testing is not performed on isolates from environmental sources.
CPT Code(s)
87186
Components
Component Test Code*Component Chart NameLOINC
0060227Susceptibility, Mould29577-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Aspergillus species
  • fungal
  • Fungal Susceptibility
  • Fungi
  • mold
  • Mould Susceptibility Panel
  • Susceptibility Testing