Antimicrobial Susceptibility - mecA/mecC Genes by PCR
Ordering Recommendation

Gold standard for detecting oxacillin/nafcillin resistance in Staphylococcus species. Determine presence of mecA/mecC genes that confer resistance to nearly all beta-lactam antibiotics. For susceptibility panel testing for Staphylococcus spp, order Antimicrobial Susceptibility - Staphylococcus (0060707). For detection of colonization, order Staphylococcus Surveillance Culture (0060124).

Qualitative Polymerase Chain Reaction
1-3 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Actively growing Staphylococcus aureus or coagulase-negative Staphylococcus, in pure culture. 
Specimen Preparation
Transport sealed container with pure culture on agar slant or in bacterial transport media. Place each specimen in an individually sealed bag. 
Storage/Transport Temperature
Room temperature. 
Unacceptable Conditions
Mixed cultures or non-viable organisms. 
Isolate identification and specimen source required. 
Ambient: 1 week; Refrigerated: 1 week; Frozen: Unacceptable 
Reference Interval
Presence or absence (of mecA/mecC genes).
Interpretive Data
Presence of mecA/mecC genes indicates resistance to methicillin/oxacillin and most other beta-lactam antibiotics.

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

An additional processing fee will be billed for all organisms not submitted in pure culture, as indicated in the specimen requirements.

If species identification is not provided, identification will be performed at ARUP. Additional charges apply.
Hotline History
Component Test Code*Component Chart NameLOINC
0060211Susceptibility, mecA/mecC48813-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • beta-lactam antibiotic resistance
  • mecA Gene
  • mecC Gene
  • MRSA