Determine the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of requested antimicrobial agent against submitted bacterial isolate. Refer to NOTE section below for list of antimicrobial agents available for testing.
- Patient Preparation
- Actively growing isolate in pure culture.
- Specimen Preparation
- Transport sealed container with pure culture on agar slant or in bacterial transport media. Place each specimen in individually sealed bag.
- Storage/Transport Temperature
- Room temperature.
- Unacceptable Conditions
- Mixed cultures or non-viable organisms.
- Isolate identification and specimen source required. Individual antibiotics must be specified.
- Ambient: 1 week; Refrigerated: Unacceptable; Frozen: Unacceptable
The MBC is defined as the lowest concentration of an antimicrobial agent needed to kill 99.9 percent of the initial organism inoculum. Presently, specific guidelines for interpretation are not available; therefore, a clinician knowledgeable in both bactericidal testing and infectious diseases should be available to interpret the results.
For serious infections with coagulase-negative staphylococci, testing for oxacillin resistance will be performed in order to interpret the results for beta-lactam agents.
This test must be ordered for each antimicrobial agent tested.
The minimum turnaround time is 48 hours for nonfastidious, rapidly growing organisms and greater than or equal to 96 hours for fastidious, slow growing organisms.
An additional processing fee will be billed for all organisms submitted that are not in pure culture as indicated in the specimen requirements.
If species identification is not provided, identification will be performed at ARUP. Additional charges apply.
|Component Test Code*||Component Chart Name||LOINC|
- Antibiotic MIC/MBC
- Minimum Bactericidal Concentration
- Minimum Inhibitory Concentration
- Minimum Inhibitory Concentration (MIC)/Minimum Bactericidal Concentration (MBC)