Antimicrobial Susceptibility - MIC/MBC
0060203
Ordering Recommendation
 
Mnemonic
MA MBC
Methodology
Broth Microdilution
Performed
Sun-Sat
Reported
2-4 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Actively growing isolate in pure culture.  
Specimen Preparation
Transport sealed container with pure culture on agar slant or in bacterial transport media.  Place each specimen in individually sealed bag.  
Storage/Transport Temperature
Room temperature.  
Unacceptable Conditions
Mixed cultures or non-viable organisms.  
Remarks
Isolate identification and specimen source required. Individual antibiotics must be specified.  
Stability
Ambient: 1 week; Refrigerated: Unacceptable; Frozen: Unacceptable  
Reference Interval
Susceptible, intermediate, or resistant.  
Interpretive Data
 
Note
The MIC is defined as the lowest concentration of an antibiotic which will inhibit the in vitro growth of an infectious organism. Results are reported in micrograms per mL. The interpretation of in vitro data is based on achievable serum concentrations, which may vary depending on dose, route of administration, degree of protein binding, site of infection, age and weight of the patient, and other factors.

The MBC is defined as the lowest concentration of an antimicrobial agent needed to kill 99.9 percent of the initial organism inoculum. Presently, specific guidelines for interpretation are not available; therefore, a clinician knowledgeable in both bactericidal testing and infectious diseases should be available to interpret the results.

For serious infections with coagulase-negative staphylococci, testing for the presence of mecA will be performed in order to interpret the results for agents.

This test must be ordered for each antimicrobial agent tested.

The minimum turnaround time is 48 hours for nonfastidious, rapidly growing organisms and greater than or equal to 96 hours for fastidious, slow growing organisms.

An additional processing fee will be billed for all organisms submitted that are not in pure culture as indicated in the specimen requirements.

If species identification is not provided, identification will be performed at ARUP. Additional charges apply.
CPT Code(s)
87186; 87187
Components
Component Test Code*Component Chart NameLOINC
0060203Susceptibility, MIC/MBC23658-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Antibiotic MIC/MBC
  • MIC/MBC
  • Minimum Bactericidal Concentration
  • Minimum Inhibitory Concentration
  • Minimum Inhibitory Concentration (MIC)/Minimum Bactericidal Concentration (MBC)