Antimicrobial Susceptibility - MIC, Individual
0060201
Ordering Recommendation
 
Mnemonic
MA MIC
Methodology
Gradient Diffusion/Broth Microdilution
Performed
Sun-Sat
Reported
1-3 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Actively growing isolate in pure culture.  
Specimen Preparation
Transport sealed container with pure culture on agar slant or in bacterial transport media.  Place each specimen in individually sealed bag.  
Storage/Transport Temperature
Room temperature.  If culture is suspected of being a microorganism listed as infectious substance affecting humans on IATA list, submit specimen according to Biological Substance, Category A, shipping guidelines.  
Unacceptable Conditions
Mixed cultures or non-viable organisms.  
Remarks
Isolate identification and specimen source required. Individual antibiotics must be specified.  
Stability
Ambient: 1 week; Refrigerated: Unacceptable; Frozen: Unacceptable  
Reference Interval
Susceptible, intermediate, or resistant.  
Interpretive Data
 
Note
The MIC is defined as the lowest concentration of an antibiotic which will inhibit the in vitro growth of an infectious organism. Results are reported in micrograms per mL. The interpretation of in vitro data is based on achievable serum concentrations, which may vary depending on dose, route of administration, degree of protein binding, site of infection, age and weight of the patient, state of health of the patient, and other factors.

Reporting of MICs can provide the physician with precise information regarding the infectious organism's degree of susceptibility. When this information is coupled with the physician's knowledge of the site and severity of the infection, as well as the pharmacology of antibiotics, a rational choice of the most appropriate antibiotic can be made to suit the individual patient. With the quantitative MIC: (1) susceptibility can be determined for dosages and routes of administration other than those usually prescribed and (2) susceptibility can more accurately be related to the achievable antibiotic concentration in urine, bile, CSF, and other body fluids which may vary widely from the achievable concentration in serum.

This test will bill per antibiotic tested. Susceptibility panels are available for certain organisms. Refer to Antimicrobial Susceptibility by organism type. For organisms where panels are not available, specific agent(s) to be tested must be indicated.

For serious infections with coagulase-negative staphylococci other than S. epidermidis, testing for the presence of mecA may be appropriate and will be performed in order to interpret the results for β-lactam agents.

Daptomycin MIC is available for testing MRSA or VRE.

An additional processing fee will be billed for all organisms not submitted in pure culture, as indicated in the specimen requirements.

If species identification is not provided, identification will be performed at ARUP. Additional charges apply.
CPT Code(s)
87181 or 87186
Components
Component Test Code*Component Chart NameLOINC
0060201Susceptiblity, Individual MIC21070-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • antibiotic MIC
  • Antibiotic MIC Susceptibility, Single Drug
  • broth microdilution
  • E Test
  • Etest
  • Minimum Inhibitory Concentration
  • Susceptibility Testing