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Mycobacterium tuberculosis by Amplified Detection, CSF (INACTIVE as of 06/02/14: Refer to 2010775)
0060063
Ordering Recommendation
Mnemonic
MC MTDCSF
Methodology
Qualitative Transcription-Mediated Amplification
Performed
Sun-Fri
Reported
1-3 days

Changed on 07/18/05 Hot Line:
Within 24 hours
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
CSF. 
Specimen Preparation
Transfer 1 mL CSF to a sterile container. (Min: 0.5 mL) 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Bloody specimens. 
Remarks
 
Stability
Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 1 week 
Reference Interval
Negative - No Mycobacterium tuberculosis complex rRNA detected by transcription-mediated amplification.
Interpretive Data
This test is not FDA approved for specimens other than respiratory sources; however, this test was validated at ARUP Laboratories for non-bloody CSF specimens.

The MTD test is specific for, but does not differentiate among members of the M. tuberculosis complex. M. celatum and M. terrae-like organisms will cross react if present at concentrations higher than 30 CFU/test. However, those species are rare clinical isolates. Specimens with high levels of nontuberculosis mycobacteria (greater than 1,000,000 cells/test) may cause low-level positive MTD results when M. tuberculosis complex is not present.

Compliance Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
CPT Code(s)
87556
Components
Component Test Code*Component Chart NameLOINC
0060063M tuberculosis Amplified Detection, CSF14561-5
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Amplified Direct Detection, MTD
  • M tuberculosis CSF PCR
  • Mycobacterium tuberculosis Detection, NAA
  • Mycobacterum tuberculosis direct
  • TB CSF PCR