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Thrombotic Risk, DNA Panel
0056200
Ordering Recommendation

Acceptable panel to detect the two most common inherited thrombophilias (prothrombin-related and factor V Leiden-related).

Mnemonic
THROMDNA
Methodology
Polymerase Chain Reaction
Performed
Sun-Sat
Reported
2-5 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Lavender (EDTA), pink (K2 EDTA) or yellow (ACD Solution A or B).  
Specimen Preparation
Transport 3 mL whole blood. (Min: 1 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Plasma or serum; collection of specimen in sodium heparin tubes.  
Remarks
 
Stability
Ambient: 72 hours; Refrigerated: 2 weeks; Frozen: 1 month.  
Reference Interval
Test Number
Components
Reference Interval
0097720Factor V Leiden (F5) R506Q MutationNegative: This sample is negative for factor V Leiden, R506Q mutation.
0055655Methylenetetrahydrofolate Reductase (MTHFR) 2 VariantsNegative: Neither of the common MTHFR gene variants tested, c.665C>T (previously designated C677T) and c.1286A>C (previously designated A1298C), were detected. Other causes of elevated homocysteine levels, coronary heart disease, or thrombosis were not assessed. This genotype is associated with a normal folate metabolism.
0056060Prothrombin (F2) G20210A MutationNegative: This sample is negative for the factor II, prothrombin 20210A mutation.


Interpretive Data


Note
CPT Code(s)
81240, 81241, 81291
Components
Component Test Code*Component Chart NameLOINC
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • FVL R506Q, MTHFR, and Factor II mutation panel
  • Hypercoag
  • Hypercoagulable Panel