Feedback
Thrombotic Risk, DNA Panel
0056200
Ordering Recommendation
Acceptable panel to detect the two most common inherited thrombophilias (prothrombin-related and factor V Leiden-related).
Mnemonic
THROMDNA
Methodology
Polymerase Chain Reaction
Performed
Sun-Sat
Reported
2-5 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Lavender (EDTA), pink (K2 EDTA) or yellow (ACD Solution A or B).  
Specimen Preparation
Transport 3 mL whole blood. (Min: 1 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Plasma or serum. Heparinized specimens.  
Remarks
  
Stability
Ambient: 72 hours; Refrigerated: 2 weeks; Frozen: 1 month.  
Reference Interval
 
 
Test Number Components Reference Interval
0097720Factor V Leiden (F5) R506Q Mutation Negative: This sample is negative for factor V Leiden, R506Q mutation.
0055655Methylenetetrahydrofolate Reductase (MTHFR) 2 Mutations Negative: Neither of the common MTHFR gene mutations tested, c.665C>T (previously designated C677T) and c.1286A>C (previously designated A1298C), were detected. Other causes of elevated homocysteine levels, coronary heart disease, or thrombosis were not assessed. This genotype is associated with a normal folate metabolism.
0056060Prothrombin (F2) G20210A Mutation Negative: This sample is negative for the factor II, prothrombin 20210A mutation.
 
Interpretive Data
 
Note
 
CPT Code(s)
81240, 81241, 81291
Components
Aliases
  • FVL R506Q, MTHFR, and Factor II mutation panel
  • Hypercoag
  • Hypercoagulable Panel