T-Cell Clonality Screening by PCR
Ordering Recommendation
Submit With Order
Polymerase Chain Reaction/Capillary Electrophoresis
DNA Isolation: Sun-Sat
Mon, Wed-Fri
5-7 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Lavender (EDTA) or bone marrow (EDTA) OR tissue.  
Specimen Preparation
Whole blood: Transport 5 mL. (Min: 1 mL)
OR Bone marrow:
Transport 3 mL. (Min: 1 mL)
OR Fresh tissue:
Freeze immediately. Transport 100 mg or 0.5-2.0 cm3 tissue
OR FFPE tumor tissue:
Formalin fix (10 percent neutral buffered formalin) and paraffin embed tissue. Protect from excessive heat. Transport tissue block or four 10-micron shavings. Tissue block will be returned after testing. Transport tissue (frozen or paraffin) in a tissue transport kit (ARUP supply #47808) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787.  
Storage/Transport Temperature
Whole blood OR Bone marrow: Refrigerated.
Fresh tissue:
Frozen on dry ice.
FFPE tumor tissue:
Room temperature or refrigerated. Ship in cooled container during summer months.  
Unacceptable Conditions
Serum. Frozen whole blood or bone marrow. Clotted or grossly hemolyzed specimens. Specimens fixed/processed in alternative fixatives or heavy metal fixatives (B-4 or B-5) or tissue sections on slides. Decalcified specimens.  
Whole blood OR Bone marrow: Ambient: 24 hours; Refrigerated: 5 days; Frozen: Unacceptable
Fresh Tissue:
Ambient: Unacceptable; Refrigerated: 2 hours; Frozen: 1 year
FFPE tumor tissue:
Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable  
Reference Interval
Interpretive Data
Refer to report.

See Compliance Statement B: www.aruplab.com/CS
CPT Code(s)
Component Test Code*Component Chart Name
0055567T-Cell Clonality by PCR
2006285T-Cell Clonality Source
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Cross References
  • T Cell Gamma
  • T Cell Gene Rearrangement
  • T-cell receptor gamma rearrangment
  • T-Cell Receptor Gene Rearrangement
  • TCRG