Autoimmune Hepatitis Panel with Reflex to ANA IFA Titer (INACTIVE as of 11/19/12: Refer to 2007209)
Ordering Recommendation
Semi-Quantitative Enzyme-Linked Immunosorbent Assay/Qualitative Enzyme-Linked Immunosorbent Assay/Semi-Quantitative Indirect Fluorescent Antibody
Sun, Tue, Thu
2-4 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Serum separator tube. 
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 1 mL) 
Storage/Transport Temperature
Unacceptable Conditions
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) 
Reference Interval
Test Number
Reference Interval
0050080Anti-Nuclear Antibodies (ANA), IgG by ELISA with Reflex to ANA, IgG by IFAEffective November 19, 2012
Components Reference Interval
Anti-Nuclear Antibodies (ANA), IgG by ELISANone Detected
Nuclear Antibody (ANA) by IFA, IgGLess than 1:40

0055248F-Actin (Smooth Muscle) Antibody, IgGEffective May 16, 2011
19 Units or lessNegative
20-30 UnitsWeak Positive - Suggest repeat testing in two to three weeks with fresh specimen.
31 Units or greaterPositive - Suggestive of autoimmune hepatitis type 1 or chronic active hepatitis.

0055241Liver-Kidney Microsome - 1 Antibody, IgG
0.0-20.0 UNegative
20.1-24.9 UEquivocal
Greater than or equal to 25.0 UPositive

0050065Mitochondrial M2 Antibody, IgG (ELISA)
20.0 Units or lessNegative
20.1-24.9 UnitsEquivocal
25.0 Units or greaterPositive

Interpretive Data

Specimens are screened for ANA using ELISA. If antibodies are detected, then an IFA titer using HEp-2 cells will be added. Additional charges apply.
CPT Code(s)
86038 ANA; if reflexed, add 86039 ANA titer if positive; 83516 F-Actin IgG; 86376 LKM-1 IgG; 83516 AMA
Component Test Code*Component Chart NameLOINC
0050065Mitochondrial (M2) Antibody, IgG14251-3
0050080Anti-Nuclear Ab (ANA), IgG by ELISA29950-3
0055241Liver-Kid Microsome-1 Ab, IgG by ELISA47318-1
0055248F-Actin (Smooth Muscle) Ab, IgG by ELISA44706-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.