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F-Actin (Smooth Muscle) Antibody, IgG
0055248
Ordering Recommendation
Mnemonic
ACTIN IGG
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Sun-Sat
Reported
Within 24 hours
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Serum separator tube  
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Urine or plasma. Contaminated, heat-inactivated, hemolyzed, icteric, or severely lipemic specimens.  
Remarks
 
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)  
Reference Interval
Effective May 16, 2011
19 Units or lessNegative
20-30 UnitsWeak Positive - Suggest repeat testing in two to three weeks with fresh specimen.
31 Units or greaterPositive - Suggestive of autoimmune hepatitis type 1 or chronic active hepatitis.

Interpretive Data
F-actin antibodies have been shown to have greater sensitivity and specificity for autoimmune liver disease than anti-smooth muscle antibodies.


Note
CPT Code(s)
83516
Components
Component Test Code*Component Chart NameLOINC
0055248F-Actin (Smooth Muscle) Ab, IgG by ELISA44706-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • ACTA
  • Actin Antibody
  • Anti-Actin Antibody
  • Anti-F-Actin Antibody
  • Anti-Smooth Muscle Antibody
  • Antiactin Antibody
  • ASMA
  • F-Actin Antibody
  • SMA