F-Actin (Smooth Muscle) Antibody, IgG
0055248
 
Ordering Recommendation
Mnemonic
ACTIN IGG
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Sun-Sat
Reported
Within 24 hours
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
 
Collect
Serum separator tube  
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Urine or plasma. Contaminated, heat-inactivated, hemolyzed, icteric, or severely lipemic specimens.  
Remarks
 
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)  
Reference Interval
Effective May 16, 2011
19 Units or less Negative
20-​30 Units Weak Positive -​ Suggest repeat testing in two to three weeks with fresh specimen.
31 Units or greater Positive -​ Suggestive of autoimmune hepatitis type 1 or chronic active hepatitis.
Interpretive Data
F-actin antibodies have been shown to have greater sensitivity and specificity for autoimmune liver disease than anti-smooth muscle antibodies.
Note
CPT Code(s)
83516
Components
Component Test Code*Component Chart Name
0055248F-Actin (Smooth Muscle) Ab, IgG by ELISA
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at interface.support@aruplab.com.
Cross References
  • ACTA
  • Actin Antibody
  • Anti-Actin Antibody
  • Anti-F-Actin Antibody
  • Anti-Smooth Muscle Antibody
  • Antiactin Antibody
  • ASMA
  • F-Actin Antibody
  • SMA