Varicella-Zoster Virus Antibody, IgM by ELISA (CSF)
0054445
Ordering Recommendation
 
Mnemonic
VZMCSF
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Mon-Fri
Reported
1-5 days  
New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
CSF.  
Specimen Preparation
Transfer 0.5 mL CSF to an ARUP Standard Transport Tube. (Min: 0.3 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Specimen types other than CSF. Contaminated or heat-inactivated specimens.  
Remarks
  
Stability
Ambient: 8 hours; Refrigerated: 2 weeks; Frozen: 1 year  
Reference Interval
0.90 ISR or less: Negative - No significant level of IgM antibody to varicella-zoster virus detected.
0.91-1.09 ISR: Equivocal - Repeat testing in 10-14 days may be helpful.
1.10 ISR or greater: Positive - Significant level of IgM antibody to varicella-zoster virus detected, which may indicate current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.  
Interpretive Data
The detection of antibodies to varicella-zoster in CSF may indicate central nervous system infection. However, consideration must be given to possible contamination by blood or transfer of serum antibodies across the blood-brain barrier.

See Compliance Statement B: www.aruplab.com/CS
Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
 
Note
 
CPT Code(s)
86787
Components
Component Test Code*Component Chart NameLOINC
0054445VZV Antibody IgM CSF31695-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Herpes Zoster
  • Varicella Zoster Virus CSF IgM
  • VZV CSF IgM