Cytomegalovirus, Quantitative PCR
0051813
Ordering Recommendation
Preferred test for detecting cytomegalovirus infection and guiding posttransplant therapy.
Mnemonic
CMV QNT
Methodology
Quantitative Polymerase Chain Reaction
Performed
Sun-Sat
Reported
1-3 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Lavender (EDTA) or pink (K2EDTA).  
Specimen Preparation
Separate plasma from cells. Transfer 1 mL plasma to a sterile container. (Min: 0.5 mL).  
Storage/Transport Temperature
Frozen.  
Unacceptable Conditions
Serum. Heparinized specimens.  
Remarks
  
Stability
Ambient: 24 hours; Refrigerated: 5 days; Frozen: 1 year  
Reference Interval
Not detected  
Interpretive Data
The quantitative range of this test is 2.6-6.6 log copies/mL (390-3,900,000 copies/mL) or 2.4-6.4 log IU/mL (227-2,270,000 IU/mL). One IU/mL of CMV DNA is approximately 1.72 copies/mL.

A negative result (less than 2.6 log copies/mL [less than 390 copies/mL] OR less than 2.4 log IU/mL [less than 227 IU/mL]) does not rule out the presence of PCR inhibitors in the patient specimen or CMV DNA concentrations below the level of detection of the test. Inhibition may also lead to underestimation of viral quantitation.

See Compliance Statement A: www.aruplab.com/CS
Statement A: Analyte specific reagents (ASR) are used in many laboratory tests necessary for standard medical care and generally do not require U.S. Food and Drug Administration (FDA) approval or clearance. This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions. This test should not be regarded as investigational or for research use.
 
Note
The limit of quantification for this DNA test is 2.6 log copies/mL (390 copies/mL) or 2.4 log IU/mL (227 IU/mL). If the test DID NOT DETECT the virus, the test result will be reported as "<2.6 log copies/mL (<390 copies/mL)" and "<2.4 log IU/mL (<227 IU/mL)."  If the test DETECTED the presence of the virus but was not able to accurately quantify the number of copies, the test result will be reported as "Not Quantified."
CPT Code(s)
87497
Components
Component Test Code*Component Chart NameLOINC
0051814Cytomegalovirus, Quant. Interp40444-2
0051815Cytomegalovirus, Quant. Log cpy/mL54206-8
2002316Cytomegalovirus, Quant. Cpy/mL30247-1
2006534Cytomegalovirus, Quant. IU/mL72493-0
2006535Cytomegalovirus, Quant. Log IU/mL72494-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • CMV Quant PCR
  • CMV quantitative
  • herpes
  • HHV-5
  • Human herpesvirus 5
  • Viral load monitoring