Hepatitis C Virus RNA Quantitative bDNA (INACTIVE as of 02/17/2015: Refer to 0098268)
Ordering Recommendation
Quantitative Branched Chain DNA
Mon, Thu
3-8 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Lavender (EDTA), pink (K2EDTA), plasma preparation tube, or serum separator tube. 
Specimen Preparation
Separate serum or plasma from cells within 4 hours. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.2 mL).
PPT: Separate plasma from cells within 2 hours. Transport 1 mL plasma in original container. (Min: 0.2 mL) 
Storage/Transport Temperature
Unacceptable Conditions
Heparinized specimens. 
PPT: On Cells: Ambient: 2 hours. All others: On cells: Ambient 4 hours. After separation from cells; Refrigerated: 48 hours; Frozen at -20°C: 72 hours; Frozen at -70°C: 4 months 
Reference Interval
Not detected
Interpretive Data
The quantitative range of this assay is 2.8-6.9 log IU/mL (615-7,690,000 IU/mL).

An interpretation of "Not Detected" does not rule out the presence of inhibitors in the patient specimen or hepatitis C virus RNA concentrations below the level of detection of the assay. Care should be taken in the interpretation of any single viral load determination. Low positive values may occasionally be seen in specimens from patients who are uninfected.

This assay should not be used for blood donor screening, associated re-entry protocols, or for screening Human Cell, Tissues and Cellular Tissue-Based Products (HCT/P).

This test is intended for use in conjunction with clinical presentation and other laboratory markers as an indicator of disease prognosis. This test is also used as an aid in assessing viral response to antiretroviral treatment as measured by changes in HCV RNA levels. A quantitative PCR assay with a detection limit of 1.2 log IU/mL (18 IU/mL), Hepatitis C Virus RNA Quantitative, Real-Time PCR (0098268), is available for the assessment of lower levels of HCV viremia.
CPT Code(s)
Component Test Code*Component Chart NameLOINC
0051812HCV RNA Quant bDNA Interpretation48576-3
0051823HCV RNA Quant bDNA, Log42617-1
2002645HCV RNA Quant bDNA, IU29609-5
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • HCV branch DNA
  • HCV quantitative
  • HCV Quantitative bDNA
  • HCV viral load
  • Signal amplification
  • Viral load monitoring