Preferred testing for herpes simplex virus (HSV) when recent acquisition of herpes simplex virus is suspected. Because glycoprotein antibodies may require 3-6 months to form, follow-up testing is recommended to confirm a negative IgG glycoprotein result in the context of positive HSV types 1 or 2 antibody results. Refer to Herpes Simplex Type 1 and Type 2 Glycoprotein G-Specific Antibodies, IgG by CIA (0051152).
- Patient Preparation
- Serum separator tube.
- Specimen Preparation
- Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of acute specimens. Mark specimens plainly as "acute" or "convalescent."
- Storage/Transport Temperature
- Unacceptable Conditions
- Plasma or urine. Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.
- Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
|Test Number||Components||Reference Interval|
| ||HERPES I/II IgG||0.89 IV or less: Negative - No significant level of detectable HSV IgG antibody.|
0.90-1.09 IV: Equivocal - Questionable presence of IgG antibodies. Repeat testing in 10-14 days may be helpful.
1.10 IV or greater: Positive - IgG antibody to HSV detected which may indicate a current or past HSV infection.
|0050292||Herpes Simplex Virus Type 1 Glycoprotein G-Specific Antibody, IgG by CIA|
|0050294||Herpes Simplex Virus Type 2 Glycoprotein G-Specific Antibody, IgG by CIA|
|Component Test Code*||Component Chart Name||LOINC|
|0050286||HSV Type 1/2 Combined Ab, IgG||27948-9|
- glycoprotein type-specific reactivity
- Herpes Simplex Antibodies, IgG
- Herpes Simplex Serology, Serum HSV 1,2
- HSV 1, 2 IgG
- HSV 1,2
- HSV 1,2 glycoprotein
- HSV glycoprotein G
- HSV glycoprotein G-based type-specific serology