Cytokine Panel, Monokines
Ordering Recommendation
Quantitative Multiplex Bead Assay
Mon, Wed, Fri
1-4 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
Serum separator tube, plain red, or green (lithium heparin).  
Specimen Preparation
Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.3 mL)  
Storage/Transport Temperature
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.  
Unacceptable Conditions
Refrigerated specimens. Contaminated or heat-inactivated specimens.  
After separation from cells: Ambient: 30 minutes; Refrigerated: Unacceptable; Frozen: 1 year  
Reference Interval
Test Number Components Reference Interval
0051536Interleukin 1 beta Effective May 19, 2014
36 pg/mL or less
0051537Interleukin 6 Effective May 19, 2014
5 pg/mL or less
0051538Interleukin 8 Effective May 19, 2014
5 pg/mL or less
0051539Tumor Necrosis Factor -​ alpha Effective May 19, 2014
22 pg/mL or less
Interpretive Data
Results are to be used for research purposes or in attempts to understand the pathophysiology of immune, infectious, or inflammatory disorders.

Compliance Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
Lower limit of detection is 5 pg/mL.
CPT Code(s)
83520 x 4
Component Test Code*Component Chart NameLOINC
0051536Interleukin 1 beta13629-1
0051537Interleukin 626881-3
0051538Interleukin 833211-4
0051539Tumor Necrosis Factor - alpha3074-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • IL-1 Beta
  • IL-6
  • IL-8
  • TNF Alpha