Deficiency in cytokine production in response to stimulation suggests possibility of defect in Interleukin-1-Receptor-Associated Kinase-4 (IRAK-4), which may result in recurrent pneumococcal and/or staphylococcal infections, in absence of other abnormalities of host defense.
Compliance Statement B
: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.