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Allergens, Upper Respiratory Disease Profile, Region 9A
Ordering Recommendation
New York DOH Approval Status
Specimen Required
Multiple patient encounters should be avoided.
Serum separator tube. Multiple specimen tubes should be avoided.
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1.65 mL serum to an ARUP Standard Transport Tube. (Min: 0.80 mL)
Refrigerated.
Hemolyzed, icteric or lipemic specimens
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
Methodology
Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay
Performed
Sun-Sat
Reported
1-3 days
Reference Interval
Effective 02/18/2014
| Reporting Range (reported in kU/L) |
Probability of IgE Mediated Clinical Reaction |
Class Scoring |
|---|---|---|
| Less than 0.10 | No significant level detected | 0 |
| 0.10 - 0.34 | Clinical relevance undetermined | 0/1 |
| 0.35 - 0.70 | Low | 1 |
| 0.71 - 3.50 | Moderate | 2 |
| 3.51 - 17.50 | High | 3 |
| 17.51 - 50.00 | Very high | 4 |
| 50.01 - 100.00 | Very high | 5 |
| Greater than 100.00 | Very high | 6 |
Interpretive Data
Allergen results of 0.10-0.34 kU/L are intended for specialist use as the clinical relevance is undetermined. Even though increasing ranges are reflective of increasing concentrations of allergen-specific IgE, these concentrations may not correlate with the degree of clinical response or skin testing results when challenged with a specific allergen. The correlation of allergy laboratory results with clinical history and in vivo reactivity to specific allergens is essential. A negative test may not rule out clinical allergy or even anaphylaxis.
FDA
Note
Allergens included: Alternaria alternata, Box Elder/Maple Tree, Cat Dander, Cottonwood Tree, D. farinae (mites), June Grass, Pigweed, Russian Thistle, Hormodendrum, Elm Tree, Oak Tree, Aspergillus fumigatus, Common Ragweed, Cockroach (German), Dog Dander.
Hotline History
CPT Codes
86003 x15
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0055001 | Allergen, Fungi/Mold, A. alternata IgE | 6020-2 |
| 0055003 | Allergen, Tree, Box Elder/Maple Tree IgE | 7155-5 |
| 0055006 | Allergen, Animal, Cat Dander IgE | 6833-8 |
| 0055010 | Allergen, Tree, Cottonwood Tree IgE | 6090-5 |
| 0055017 | Allergen, Grass, June/Kentucky Blue IgE | 6153-1 |
| 0055025 | Allergen, Weed, Pigweed IgE | 7604-2 |
| 0055027 | Allergen, Weed, Russian Thistle IgE | 6234-9 |
| 0055038 | Allergen, Fungi/Mold, Hormodendrum IgE | 6075-6 |
| 0055041 | Allergen, Interp, Immunocap Score IgE | 48767-8 |
| 0055042 | Allergen, Tree, Elm Tree IgE | 6109-3 |
| 0055045 | Allergen, Tree, Oak Tree IgE | 6189-5 |
| 0055061 | Allergen, Fungi/Mold, A. fumigatus IgE | 6025-1 |
| 0055064 | Allergen, Mites, D. farinae IgE | 6095-4 |
| 0055085 | Allergen, Weed, Common/Short Ragweed IgE | 6085-5 |
| 0055088 | Allergen, Insect, Cockroach, German IgE | 6078-0 |
| 0099568 | Allergen, Animal, Dog Dander IgE | 6098-8 |
